Immunology of normal pregnancy

被引：124

作者：

Aagaard-Tillery, Kjersti M. ^{[1
]}

Silver, Robert ^{[1
]}

Dalton, Jess ^{[1
]}

机构：

[1] Univ Utah Hlth Sci, Dept Obstet & Gynecol, Div Maternal Fetal Med, Salt Lake City, UT 84132 USA

来源：

SEMINARS IN FETAL & NEONATAL MEDICINE | 2006年 / 11卷 / 05期

关键词：

immune response; pregnancy; human; immunology; cytokines; leukocytes; placenta;

D O I：

10.1016/j.siny.2006.04.003

中图分类号：

R72 [儿科学];

学科分类号：

100202 [儿科学];

摘要：

Since Medawar's initial contemplations in 1953 on the mechanisms of immune evasion allowing for the survival of the allogeneic conceptus in an immunologically competent mother, physicians and immunologists alike have struggled to understand the immunological paradox of pregnancy. Ultimately, our attempts to define the immunology of normal pregnancy have broadened our appreciation of the myriad mechanisms at play that enable the promotion of implantation and maintenance of pregnancy. In this review, we summarise what is known regarding the immunology of normal pregnancy, with special emphasis on the relation to common disorders of pregnancy. (c) 2006 Elsevier Ltd. All rights reserved.

引用

页码：279 / 295

页数：17

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