A simple method to polyhydroxylated olefinic molecules using ring-closing olefin metathesis

被引：106

作者：

Chang, SB ^{[1
]}

Grubbs, RH ^{[1
]}

机构：

[1] CALTECH,ARNOLD & MABEL BECKMAN LABS CHEM SYNTHESIS,DIV CHEM & CHEM ENGN,PASADENA,CA 91125

来源：

TETRAHEDRON LETTERS | 1997年 / 38卷 / 27期

关键词：

D O I：

10.1016/S0040-4039(97)01031-9

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

This paper describes the ring-closing metathesis of silyl ether connected dienes using molybdenum and ruthenium alkylidene catalysts. The cyclizations proceed to afford the corresponding cyclic silyloxy olefins in good to excellent yields. Subsequent oxidative ring cleavage yields highly functionalized olefins. (C) 1997 Elsevier Science Ltd.

引用

页码：4757 / 4760

页数：4

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