Protective effects of Gynostemma pentaphyllum in gamma-irradiated mice

被引:11
作者
Chen, WC [1 ]
Hau, DM [1 ]
Chen, KT [1 ]
Wang, MI [1 ]
Lin, IH [1 ]
机构
[1] NATL TSING HUA UNIV,INST RADIAT BIOL,HSINCHU,TAIWAN
来源
AMERICAN JOURNAL OF CHINESE MEDICINE | 1996年 / 24卷 / 01期
关键词
D O I
10.1142/S0192415X96000116
中图分类号
R [医药、卫生];
学科分类号
10 [医学];
摘要
Radiation protective effects of Gynostemma Pentaphyllum (Gp) were investigated in gamma-irradiated mice. Animals were sacrificed on days 5, 15, 25 and 35 after gamma-irradiation. GOT, GPT, serum IgG and leukocyte counts were measured. Proliferation of splenocytes stimulated by mitogens, such as PHA, Con A, and LPS were detected and compared. The results showed that all parameters measured in this study were decreased and proliferation of splenocytes stimulated by mitogens were repressed in gamma-irradiated mice. Gp helped to recover the decreased leukocyte counts, GOT, GPT and IgG in serum and the proliferation of splenocytes stimulated by PHA, LPS and Con A in the gamma-ray irradiated mice.
引用
收藏
页码:83 / 92
页数:10
相关论文
共 29 条
[1]
EXCESSIVE INTAKE OF ZINC IMPAIRS IMMUNE-RESPONSES [J].
CHANDRA, RK .
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 1984, 252 (11) :1443-1446
[2]
CHANG JC, 1990, CHIN W MED, V10, P96
[3]
CHENG KY, 1977, CHIN J RADIOL, V2, P311
[4]
ENDRE L, 1975, LANCET, V1, P1196
[5]
EFFECT OF ZINC-DEFICIENCY ON IMMUNE-RESPONSE OF YOUNG-ADULT A-J MOUSE [J].
FRAKER, PJ ;
HAAS, SM ;
LUECKE, RW .
JOURNAL OF NUTRITION, 1977, 107 (10) :1889-1895
[6]
GUIRALDES E, 1975, LANCET, V2, P710
[7]
HAU DM, 1980, ACUP RES Q, V4, P21
[8]
HSU DM, 1989, NUCL SCI J, V26, P278
[9]
PRELIMINARY-STUDY ON ANTIRADIATION EFFECT OF KUEI-PI-TANG [J].
HSU, HY ;
HO, YH ;
LIAN, SL ;
LIN, CC .
AMERICAN JOURNAL OF CHINESE MEDICINE, 1991, 19 (3-4) :275-284
[10]
EFFECTS OF KUEI-PI-TANG ON CELLULAR IMMUNOCOMPETENCE OF GAMMA-IRRADIATED MICE [J].
HSU, HY ;
HAU, DM ;
LIN, CC .
AMERICAN JOURNAL OF CHINESE MEDICINE, 1993, 21 (02) :151-158