Successful Rescue of a Patient with Acute Aconitine Poisoning Complicated by Polycystic Renal Hemorrhage

被引:15
作者
Chen, Xinguo [1 ]
Wu, Ruike [1 ]
Jin, Huanzhi [1 ]
Gao, Renxian [1 ]
Yang, Baohua [1 ]
Wang, Qian [1 ]
机构
[1] Wenzhou Peoples Hosp, Dept Emergency Med, Wenzhou 325000, Peoples R China
关键词
aconitine poisoning; polycystic kidney hemorrhage; blood purification; ALKALOIDS;
D O I
10.1272/jnms.82.257
中图分类号
R5 [内科学];
学科分类号
100201 [内科学];
摘要
Introduction: Aconitine is a highly toxic diterpenoid alkaloid, produced by plants of the Aconitum genus, that is still used in Chinese herbal medicines. Aconitine poisoning remains common in China and other parts of Asia. Case Report: A 48-year-old man received a diagnosis of aconitine poisoning after ingesting herbal medicinal wine made with caowu, which is made from Aconitum kusnezoffii roots, and was admitted to our hospital's emergency department. Electrocardiography and thoracoabdominal computed tomography showed cardiovascular toxicity from aconitine poisoning along with polycystic renal hemorrhaging. Because the arrhythmia was not controlled with lidocaine, blood purification with a reduced dosage of heparin was performed to treat the arrhythmia and to avoid increasing the bleeding of the polycystic renal hemorrhage. The patient recovered from aconitine poisoning and polycystic kidney hemorrhage. Conclusions: This case significantly advances our understanding of hemoperfusion with reduced heparin for the treatment of ventricular arrhythmia caused by aconitine poisoning.
引用
收藏
页码:257 / 261
页数:5
相关论文
共 16 条
[1]
Cao YJ, 2011, HELONGJIANG MED SCI, V34, P109
[2]
Causes and prevention of herb-induced aconite poisonings in Asia [J].
Chan, Thomas Y. K. .
HUMAN & EXPERIMENTAL TOXICOLOGY, 2011, 30 (12) :2023-2026
[3]
Aconite poisoning presenting as hypotension and bradycardia [J].
Chan, Thomas Y. K. .
HUMAN & EXPERIMENTAL TOXICOLOGY, 2009, 28 (12) :795-797
[4]
Aconite poisoning [J].
Chan, Thomas Y. K. .
CLINICAL TOXICOLOGY, 2009, 47 (04) :279-285
[5]
CHAN TYK, 1994, VET HUM TOXICOL, V36, P326
[6]
Chang HM, 1987, PHARM APPL CHINESE M, P668
[7]
Aconitum sp. alkaloids: the modulation of voltage-dependent Na+ channels, toxicity and antinociceptive properties [J].
Friese, J ;
Gleitz, J ;
Gutser, UT ;
Heubach, JF ;
Matthiesen, T ;
Wilffert, B ;
Selve, N .
EUROPEAN JOURNAL OF PHARMACOLOGY, 1997, 337 (2-3) :165-174
[8]
Clinical features and management of herb-induced aconitine poisoning [J].
Lin, CC ;
Chan, TYK ;
Deng, JF .
ANNALS OF EMERGENCY MEDICINE, 2004, 43 (05) :574-579
[9]
Ohuchi S, 2000, Kyobu Geka, V53, P541
[10]
Pu XJ, 2006, CHINESE PHARM CLIN, V9, P713