The absolute configuration of the four stereoisomers of trans-anethole diol (1-(4'-methoxyphenyl)-1,2-propanediol), a metabolite of anethole in the rat

被引：29

作者：

Ishida, T

Bounds, SVJ

Caldwell, J

Drake, A

Takeshita, M

机构：

[1] UNIV LONDON BIRKBECK COLL,DEPT CHEM,LONDON WC1E 0AJ,ENGLAND

[2] TOHOKU COLL PHARMACEUT SCI,SENDAI,MIYAGI 981,JAPAN

[3] ST MARYS HOSP,UNIV LONDON IMPERIAL COLL SCI TECHNOL & MED,SCH MED,LONDON W2 1PG,ENGLAND

来源：

TETRAHEDRON-ASYMMETRY | 1996年 / 7卷 / 11期

关键词：

D O I：

10.1016/0957-4166(96)00411-9

中图分类号：

O61 [无机化学];

学科分类号：

070301 [无机化学]; 081704 [应用化学];

摘要：

The four stereoisomers of anethole diol, one of the major neutral metabolites of trans-anethole in the rat, have been separated by HPLC of their camphanyl esters and characterized by H-1-NMR and CD spectroscopy. Their configurations were determined by comparison of their CD spectra with those of the 1-phenylpropane-1,2-diols. Copyright (C) 1996 Elsevier Science Ltd

引用

页码：3113 / 3118

页数：6

共 14 条

[1]

BOUNDS SVJ, 1994, THESIS IMPERIAL COLL

[2]

CALDWELL J, 1991, P TOX FOR ANN SUMM M, P613

[3]

CALDWELL J, 1993, PROGR REPORT TRANSAN

[4]

CRITTERIO H, 1983, J CHEM SOC PERK T, P891