Hyponatremia in heart failure

被引:72
作者
Farmakis, Dimitrios [1 ]
Filippatos, Gerasimos [1 ]
Parissis, John [1 ]
Kremastinos, Dimitrios Th. [1 ]
Gheorghiade, Mihai [2 ]
机构
[1] Attikon Univ Hosp, Dept Cardiol 2, Heart Failure Unit, Athens, Greece
[2] Northwestern Univ, Feinberg Sch Med, Chicago, IL 60611 USA
关键词
Hyponatremia; Heart failure; Vasopressin; Tolvaptan; Conivaptan; Lixivaptan; RANDOMIZED CONTROLLED-TRIAL; VASOPRESSIN ANTAGONIST; INTRAVENOUS MILRINONE; HOSPITALIZED-PATIENTS; ARGININE-VASOPRESSIN; RISK STRATIFICATION; SERUM SODIUM; TOLVAPTAN; HYPERNATREMIA; MORTALITY;
D O I
10.1007/s10741-008-9109-7
中图分类号
R5 [内科学];
学科分类号
100201 [内科学];
摘要
Hyponatremia is the most common electrolyte abnormality found in hospitalized patients with heart failure. It may occur in patients who have hypovolemic, hypervolemic, or euvolemic state. It is usually not corrected by available therapies. It is a major predictor of prognosis, and correction of hyponatremia can be effectively accomplished by vasopressin antagonists. However, it still remains to be seen whether the normalization of serum sodium with vasopressin antagonists will also lead to an improved long-term prognosis.
引用
收藏
页码:59 / 63
页数:5
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