Antimicrobial susceptibility of invasive isolates of Streptococcus pneumoniae in Ireland

被引:5
作者
Clarke, P
Murchan, S
Smyth, EG
Humphreys, H
机构
[1] Beaumont Hosp, Royal Coll Surg Ireland, Educ & Res Ctr, Dept Clin Microbiol, Dublin 9, Ireland
[2] Beaumont Hosp, Natl Dis Surveillance Ctr, Dublin 9, Ireland
[3] Beaumont Hosp, Dept Microbiol, Dublin 9, Ireland
关键词
antimicrobial susceptibility; penicillin; resistance; Streptococcus pneumoniae;
D O I
10.1111/j.1469-0691.2004.00894.x
中图分类号
R51 [传染病];
学科分类号
100401 ;
摘要
Between January 1999 and June 2002, 646 invasive isolates of Streptococcus pneumoniae were collected in Ireland. MICs of penicillin, ciprofloxacin, cefotaxime, moxifloxacin and linezolid were determined by Etest methodology. Eighty-seven (13.5%) isolates showed intermediate resistance to penicillin, while seven (1.1%) showed high-level resistance. Eighty-seven (13.5%) isolates were resistant to erythromycin, but all isolates were susceptible to cefotaxime, moxifloxacin and linezolid. The prevalence of pneumococcal isolates non-susceptible to penicillin in Ireland is worryingly high, but currently there are alternative agents available to treat invasive infection.
引用
收藏
页码:657 / 659
页数:3
相关论文
共 15 条
[1]   Penicillin susceptibility and epidemiological typing of invasive pneumococcal isolates in the Republic of Ireland [J].
Bennett, D ;
Lennon, B ;
Humphreys, H ;
Cafferkey, M .
JOURNAL OF CLINICAL MICROBIOLOGY, 2003, 41 (08) :3641-3648
[2]  
*BRIT SOC ANT CHEM, 2001, J ANTIMICROB CHE SS1, V48, P1
[3]   A European study on the relationship between antimicrobial use and antimicrobial resistance [J].
Bronzwaer, SLAM ;
Cars, O ;
Buchholz, U ;
Mölstad, S ;
Goettsch, W ;
Veldhuijzen, IK ;
Kool, JL ;
Sprenger, MJW ;
Degener, JE .
EMERGING INFECTIOUS DISEASES, 2002, 8 (03) :278-282
[4]   Oxazolidinone antibiotics [J].
Diekema, DJ ;
Jones, RN .
LANCET, 2001, 358 (9297) :1975-1982
[5]  
*EUR ANT RES SURV, PROP PNSP IS PART CT
[6]   Penicillin resistance in pneumococci [J].
Felmingham, D ;
Tesfaslasie, Y ;
Burley, C ;
Masterton, RG .
JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, 2000, 45 (05) :710-711
[7]   Clinical outcomes of meningitis caused by Streptococcus pneumoniae in the era of antibiotic resistance [J].
Fiore, AE ;
Moroney, JF ;
Farley, MM ;
Harrison, LH ;
Patterson, JE ;
Jorgensen, JH ;
Cetron, M ;
Kolczak, MS ;
Breiman, RF ;
Schuchat, A .
CLINICAL INFECTIOUS DISEASES, 2000, 30 (01) :71-77
[8]   Fluoropuinolone resistance among Gram-positive cocci [J].
Hooper, DC .
LANCET INFECTIOUS DISEASES, 2002, 2 (09) :530-538
[9]   Surveillance of invasive Streptococcus pneumoniae infection in the province of Quebec, Canada, from 1996 to 1998:: Serotype distribution, antimicrobial susceptibility, and clinical characteristics [J].
Jetté, LP ;
Delage, G ;
Ringuette, L ;
Allard, R ;
De Wals, P ;
Lamothe, F ;
Loo, V .
JOURNAL OF CLINICAL MICROBIOLOGY, 2001, 39 (02) :733-737
[10]   Activity of linezolid against multi-resistant Gram-positive bacteria from diverse hospitals in the United Kingdom [J].
Johnson, AP ;
Warner, M ;
Livermore, DM .
JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, 2000, 45 (02) :225-230