Reconstruction of the sellar floor using Bioglue following transsphenoidal procedures

Objective. Cerebrospinal fluid rhinorrhea, pneumocephalus and meningitis are serious complications following transsphenoidal excision of sellar, suprasellar and parasellar lesions. This study evaluates the use of a new bioadhesive, Bioglue as an adjunct in reconstructing the sellar floor and preventing CSF fistula and investigates the possible complications associated with its use. Methods. In thirty-two patients (31 pituitary adenomas and 1 meningioma) Bioglue was used to help reconstruct the sellar floor after endonasal transsphenoidal procedures between January 2001 and April 2002 at the Royal Melbourne Hospital. Results. There were no post-operative CSF rhinorrhea, allergic rhinitis, meningitis, pneumocranium, granulomas or other complications associated with the use of Bioglue. Conclusion. This technique of reconstruction of seller floor using Bloglue is simple and time efficient in preventing C-SF fistula formation following transsphenoidal procedures for sellar region lesions. (C) 2002 Published by Elsevier Science Ltd.