Gastric oncology: an update

被引:19
作者
Hyatt, Benjamin J. [1 ]
Paull, Peter E.
Wassef, Wahid [1 ]
机构
[1] Univ Massachusetts, Sch Med, Div Gastroenterol, Worcester, MA 01655 USA
关键词
chromoendoscopy; confocal laser endomicroscopy; endoscopic ultrasound; gastric oncology; magnification endoscopy; ENDOSCOPIC SUBMUCOSAL DISSECTION; FINE-NEEDLE-ASPIRATION; INDIGO CARMINE DYE; MUCOSAL RESECTION; ACETIC-ACID; HELICOBACTER-PYLORI; EARLY-DIAGNOSIS; CANCER; CHROMOENDOSCOPY; LYMPHOMA;
D O I
10.1097/MOG.0b013e328331b5c9
中图分类号
R57 [消化系及腹部疾病];
学科分类号
摘要
Purpose of review As the field of endoscopy progresses, new tools and techniques continue to be developed for gastroenterology in general and gastrointestinal oncology in particular. Some of these include enhancements in diagnostic optics such as chromoendoscopy, magnification endoscopy, and confocal laser endomicroscopy. Others include advanced therapeutics such as endoscopis mucosal resection and endoscopis submucosal dissection. In this review, we will update the reader on these latest of technologies, their benefits and risks, as well as their role in evaluating, staging, and treating gastric neoplasms, especially gastric adenocarcinoma, gastrointestinal stromal tumors, and primary gastric lymphoma. Recent findings Noteworthy studies in this review indicate that in properly selected patients with gastric adenocarcinoma, endoscopic submucosal dissection is a viable alternative to gastric resection with 100% 5-year survival rates; in patients with metastatic gastrointestinal stromal tumors, imatinib can provide effective treatment with reasonable outcome; and in patients with low grade mucosa-associated lymphoid tissue lymphoma, eradication therapy with antibiotics is curative with a very low recurrence rate. Summary The advances discussed in this review have significantly improved the care we can offer our patients in gastric oncology. With continued advancement in the field, it will be crucial to continue to study outcomes and safety of these techniques and to develop structured training for those looking to perform these procedures.
引用
收藏
页码:570 / 578
页数:9
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