A novel, high-yielding synthesis of meso-substituted porphyrins via the direct arylation of porphine

被引：32

作者：

Shi, DF

Wheelhouse, RT ^{[1
]}

机构：

[1] Univ Bradford, Sch Pharm, Bradford BD7 1DP, W Yorkshire, England

[2] Univ Texas, Coll Pharm, Austin, TX 78712 USA

来源：

TETRAHEDRON LETTERS | 2002年 / 43卷 / 51期

关键词：

porphyrin; Suzuki coupling reactions; palladium;

D O I：

10.1016/S0040-4039(02)02339-0

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A new method for the synthesis of meso-substituted porphyrins is described: reaction of 5,10,15,20-tetrabromoporphine magnesium complex with aryl or heteroaryl boronic acids in the presence of Pd(PPh3)(4) gave meso-substituted porphyrins in yields up to 70%. (C) 2002 Elsevier Science Ltd. All rights reserved.

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收藏

页码：9341 / 9342

页数：2

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