Structure and dynamics of molecular motors

被引:26
作者
Amos, LA [1 ]
Cross, RA [1 ]
机构
[1] MARIE CURIE MOL MOTORS GRP,OXTED RH8 0TE,SURREY,ENGLAND
关键词
D O I
10.1016/S0959-440X(97)80032-2
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
The structures of the oppositely directed microtubule motors kinesin and ncd have been solved to atomic resolution. The two structures are very similar and are also homologous to myosin. Myosins and kinesins differ kinetically but, tantalizingly, cryoelectron microscopy has recently revealed that both structures may tilt during ADP release. Such evidence suggests that the two motor families use common structural mechanisms.
引用
收藏
页码:239 / 246
页数:8
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