The role of peptide YY in regulating glucose homeostasis

被引：55

作者：

Boey, Dana ^{[1
]}

Sainsbury, Amanda ^{[1
]}

Herzog, Herbert ^{[1
]}

机构：

[1] St Vincents Hosp, Garvan Inst Med Res, Neurosci Res Program, Darlinghurst, NSW 2010, Australia

来源：

PEPTIDES | 2007年 / 28卷 / 02期

基金：

英国医学研究理事会;

关键词：

peptide YY; glucose; insulin; type II diabetes;

D O I：

10.1016/j.peptides.2006.07.031

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The gut-derived hormone peptide YY (PYY) is most commonly known for its effect on satiety, decreasing food intake and body weight in animals and humans. However, PYY is also involved in a wide range of digestive functions including regulating insulin secretion and glucose homeostasis. Over the last few years, there have been several interesting clinical and animal studies investigating the role of PYY in glucose homeostasis. This review aims to present an updated summary of findings over the last few decades highlighting the role of PYY in regulating insulin output and insulin sensitivity, and the potential mechanisms involved. (c) 2007 Elsevier Inc. All rights reserved.

引用

页码：390 / 395

页数：6

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