Multivalent Manno-Glyconanoparticles Inhibit DC-SIGN-Mediated HIV-1 Trans-infection of Human T Cells

被引：98

作者：

Martinez-Avila, Olga ^{[2
]}

Bedoya, Luis M. ^{[1
]}

Marradi, Marco ^{[2
]}

Clavel, Caroline ^{[2
]}

Alcami, Jose ^{[1
]}

Penades, Soledad ^{[2
]}

机构：

[1] Inst Salud Carlos III, Natl Ctr Microbiol, AIDS Immunopathol Unit, Madrid, Spain

[2] CIC BiomaGUNE CIBER BBN, Lab GlycoNanotechnol, San Sebastian 20009, Spain

来源：

CHEMBIOCHEM | 2009年 / 10卷 / 11期

关键词：

gold glyconanoparticles; HIV; inhibitors; mannose; multivalency; oligosaccharides; SELECTIVE RECOGNITION; STRUCTURAL BASIS; BINDING; ORGANIZATION; MECHANISM; DENDRONS; 2G12;

D O I：

10.1002/cbic.200900294

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

[No abstract available]

引用

页码：1806 / 1809

页数：4

共 26 条

[1] Carbohydrate-mediated targeting of antigen to dendritic cells leads to enhanced presentation of antigen to T cells [J].

Adams, Eddie W. ;

Ratner, Daniel M. ;

Seeberger, Peter H. ;

Hacohen, Nir .

CHEMBIOCHEM, 2008, 9 (02) :294-303

[2] Carbohydrate-binding agents efficiently prevent dendritic cell-specific intercellular adhesion molecule-3-grabbing nonintegrin (DC-SIGN)-directed HIV-1 transmission to T lymphocytes [J].

Balzarini, Jan ;

Van Herrewege, Yven ;

Vermeire, Kurt ;

Vanham, Guido ;

Schols, Dominique .

MOLECULAR PHARMACOLOGY, 2007, 71 (01) :3-11

[3] Gold glyconanoparticles:: Synthetic polyvalent ligands mimicking glycocalyx-like surfaces as tools for glycobiological studies [J].

Barrientos, AG ;

de la Fuente, JM ;

Rojas, TC ;

Fernández, A ;

Penadés, S .

CHEMISTRY-A EUROPEAN JOURNAL, 2003, 9 (09) :1909-1921

[4] Inhibition of HIV fusion with multivalent gold nanoparticles [J].

Bowman, Mary-Catherine ;

Ballard, T. Eric ;

Ackerson, Christopher J. ;

Feldheim, Daniel L. ;

Margolis, David M. ;

Melander, Christian .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2008, 130 (22) :6896-+

[5] Glyconanoparticles:: Types, synthesis and applications in glycoscience, biomedicine and material science [J].

De la Fuente, JM ;

Penadés, S .

BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS, 2006, 1760 (04) :636-651

[6] Influence of Ligand Valency on the Targeting of Immature Human Dendritic Cells by Mannosylated Liposomes [J].

Espuelas, Socorro ;

Thumann, Christine ;

Heurtault, Beatrice ;

Schuber, Francis ;

Frisch, Benoit .

BIOCONJUGATE CHEMISTRY, 2008, 19 (12) :2385-2393

[7] Structural basis for selective recognition of oligosaccharides by DC-SIGN and DC-SIGNR [J].

Feinberg, H ;

Mitchell, DA ;

Drickamer, K ;

Weis, WI .

SCIENCE, 2001, 294 (5549) :2163-2166

[8] Candidate polyanion microbicides inhibit HIV-1 infection and dissemination pathways in human cervical explants [J].

Fletcher, Patricia S. ;

Wallace, Gregory S. ;

Mesquita, Pedro M. M. ;

Shattock, Robin J. .

RETROVIROLOGY, 2006, 3 (1)

[9] Oligolysine-based oligosaccharide clusters - Selective recognition and endocytosis by the mannose receptor and dendritic cell-specific intercellular adhesion molecule 3 (ICAM-3)-grabbing nonintegrin [J].

Frison, N ;

Taylor, ME ;

Soilleux, E ;

Bousser, MT ;

Mayer, R ;

Monsigny, M ;

Drickamer, K ;

Roche, AC .

JOURNAL OF BIOLOGICAL CHEMISTRY, 2003, 278 (26) :23922-23929

[10] A new strategy based on recombinant viruses as a tool for assessing drug susceptibility of human immunodeficiency virus type 1 [J].

Garcia-Perez, J. ;

Sanchez-Palomino, S. ;

Perez-Olmeda, M. ;

Fernandez, B. ;

Alcami, J. .

JOURNAL OF MEDICAL VIROLOGY, 2007, 79 (02) :127-137

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