The binary pyrene/heptakis-(6-amino-6-deoxy)-β-cyclodextrin complex:: a suitable chiral discriminator.: Spectrofluorimetric study of the effect of some α-amino acids and esters on the stability of the binary complex

被引：14

作者：

D'Anna, F ^{[1
]}

Riela, S ^{[1
]}

Lo Meo, P ^{[1
]}

Gruttadauria, M ^{[1
]}

Noto, R ^{[1
]}

机构：

[1] Dipartimento Chim Organ E Paterno, I-90128 Palermo, Italy

来源：

TETRAHEDRON-ASYMMETRY | 2002年 / 13卷 / 16期

关键词：

D O I：

10.1016/S0957-4166(02)00418-4

中图分类号：

O61 [无机化学];

学科分类号：

070301 [无机化学]; 081704 [应用化学];

摘要：

The effect of some alpha-amino acids and their esters on the stability of the binary pyrene/heptakis-(6-amino-6-deoxy)-beta-cyclodextrin (py/am-beta-CD) complex has been studied by means of fluorescence spectroscopy at two pH values (8.0 and 9.0). The binary complex was generally stabilized by adding the ternary agent at pH 8.0. A more varied substrate effect is observed at pH 9.0 where am-beta-CD is present in the uncharged form. The conditional constant (beta(2)) values determined by L/D alpha-amino acids show that the binary complex is a suitable receptor for chiral recognition. The enantiomer selectivity values obtained, ranging from 1.2 up to 7.4, are generally higher than those reported for alpha-amino acids and their derivatives by modified cyclodextrins. (C) 2002 Elsevier Science Ltd. All rights reserved.

引用

页码：1755 / 1760

页数：6

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