Biocompatibility and antibacterial activity of chitosan and hyaluronic acid immobilized polyester fibers

被引：29

作者：

Jou, Chi-Hsiung

Yuan, Ling

Lin, Shang-Ming

Hwang, Mou-Chuan

Chou, Wen-Li

Yu, Da-Guang

Yang, Ming-Chien ^{[1
]}

机构：

[1] Natl Taiwan Univ Sci & Technol, Dept Polymer Engn, Taipei 10672, Taiwan

[2] Nanya Inst Technol, Dept Text Sci, Chungli 32091, Taoyuan, Taiwan

[3] Taiwan Text Res Inst, Dept Raw Mat & Yarn Format, Tucheng 23674, Taipei, Taiwan

[4] Oriental Inst Technol, Dept Mat & Text, Pan Chiao 220640, Taipei, Taiwan

来源：

JOURNAL OF APPLIED POLYMER SCIENCE | 2007年 / 104卷 / 01期

关键词：

biocompatibility; polyesters; modification; polysaccharides;

D O I：

10.1002/app.25549

中图分类号：

O63 [高分子化学（高聚物）];

学科分类号：

070305 ; 080501 ; 081704 ;

摘要：

Poly(ethylene terephthalate) (PET) fibers were treated with Co-60-gamma-ray and grafted with acrylic acid. The resulting fibers were further grafted with chitosan (CS) via esterification. Afterward, hyaluronic acid (HA) was immobilized onto CS-grafting fibers. The antibacterial activity of CS against S. aureus, E. coli, and P. aeruginosa was preserved after HA-immobilization. After immobilizing HA, the L929 fibroblasts cell proliferation was improved for CS-grafting PET fiber. The results indicate that by grafting with CS and immobilizing with HA, PET fibers not only exhibit antibacterial activity, but also improve the cell proliferation for fibroblast. (c) 2007 Wiley Periodicals, Inc.

引用

页码：220 / 225

页数：6

共 26 条

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