Glucagon-like peptide-1 therapy and the exocrine pancreas: innocent bystander or friendly fire?

被引:45
作者
Butler, P. C. [1 ]
Matveyenko, A. V. [1 ]
Dry, S. [1 ]
Bhushan, A. [1 ]
Elashoff, R. [1 ]
机构
[1] Univ Calif Los Angeles, David Geffen Sch Med, Larry Hillblom Islet Res Ctr, Los Angeles, CA 90024 USA
关键词
GLP-1; Glucagon-like peptide-1; Pancreatic cancer; Pancreatitis; Type; 2; diabetes; HEREDITARY PANCREATITIS; EXENATIDE; RISK; MECHANISMS; GENE; SITAGLIPTIN; EXPRESSION; MUTATIONS; DISEASE; MODIFY;
D O I
10.1007/s00125-009-1591-5
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
引用
收藏
页码:1 / 6
页数:6
相关论文
共 38 条
[1]  
[Anonymous], SIT MARK JAN JAN AC
[2]   Notch signalling controls pancreatic cell differentiation [J].
Apelqvist, Å ;
Li, H ;
Sommer, L ;
Beatus, P ;
Anderson, DJ ;
Honjo, T ;
de Angelis, MH ;
Lendahl, U ;
Edlund, H .
NATURE, 1999, 400 (6747) :877-881
[3]   EXENATIDE-INDUCED ACUTE PANCREATITIS [J].
Ayoub, Walaa A. ;
Kumar, Ashok A. ;
Naguib, Hossam S. ;
Taylor, Harris C. .
ENDOCRINE PRACTICE, 2010, 16 (01) :80-83
[4]   Mechanisms of parenchymal injury and signaling pathways in ectatic ducts of chronic pancreatitis: implications for pancreatic carcinogenesis [J].
Bhanot, Umesh K. ;
Moeller, Peter .
LABORATORY INVESTIGATION, 2009, 89 (05) :489-497
[5]   Liraglutide once a day versus exenatide twice a day for type 2 diabetes: a 26-week randomised, parallel-group, multinational, open-label trial (LEAD-6) [J].
Buse, John B. ;
Rosenstock, Julio ;
Sesti, Giorgio ;
Schmidt, Wolfgang E. ;
Montanya, Eduard ;
Brett, Jason H. ;
Zychma, Marcin ;
Blonde, Lawrence .
LANCET, 2009, 374 (9683) :39-47
[6]   Pancreatic duct replication is increased with obesity and type 2 diabetes in humans [J].
Butler, A. E. ;
Galasso, R. ;
Matveyenko, A. ;
Rizza, R. A. ;
Dry, S. ;
Butler, P. C. .
DIABETOLOGIA, 2010, 53 (01) :21-26
[7]   Past medical conditions and K-ras mutations in pancreatic ductal adenocarcinoma: a hypothesis-generating study [J].
Crous-Bou, Marta ;
Porta, Miquel ;
Morales, Eva ;
Lopez, Tomas ;
Carrato, Alfredo ;
Puigdomenech, Elisa ;
Real, Francisco X. .
CANCER CAUSES & CONTROL, 2009, 20 (05) :591-599
[8]  
Cure P, 2008, NEW ENGL J MED, V358, P1969, DOI 10.1056/NEJMc0707137
[9]   The influence of glucose-lowering therapies on cancer risk in type 2 diabetes [J].
Currie, C. J. ;
Poole, C. D. ;
Gale, E. A. M. .
DIABETOLOGIA, 2009, 52 (09) :1766-1777
[10]   Exenatide (Exendin-4)-induced pancreatitis - A case report [J].
Denker, PS ;
Dimarco, PE .
DIABETES CARE, 2006, 29 (02) :471-471