Function and regulation of macroautophagy in plants

被引:86
作者
Bassham, Diane C. [1 ]
机构
[1] Iowa State Univ, Dept Genet Dev & Cell Biol, Ames, IA 50011 USA
来源
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH | 2009年 / 1793卷 / 09期
基金
美国国家科学基金会;
关键词
Autophagy; Stress; Pathogen; TOR; Arabidopsis; Programmed cell death; PROGRAMMED CELL-DEATH; ARABIDOPSIS HOMOLOG; CONJUGATION SYSTEM; POLLEN GERMINATION; CULTURE CELLS; RAPAMYCIN TOR; S6; KINASE; AUTOPHAGY; PROTEIN; STRESS;
D O I
10.1016/j.bbamcr.2009.01.001
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
The plant vacuole is a major site for the degradation of macromolecules, which are transferred from the cytoplasm by autophagy via double-membrane vesicles termed autophagosomes. Autophagy functions at a basal level under normal growth conditions and is induced during senescence and upon exposure to stress conditions to recycle nutrients or degrade damaged proteins and organelles. Autophagy is also required for the regulation of programmed cell death as a response to pathogen infection and possibly during certain developmental processes. Little is known about how autophagy is regulated under these different conditions in plants, but recent evidence suggests that plants contain a functional TOR pathway which may control autophagy induction in conjunction with hormonal and/or environmental signals. (C) 2009 Elsevier B.V. All rights reserved.
引用
收藏
页码:1397 / 1403
页数:7
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