Synthesis of 5H-thiazolo[3,2-a]pyrimidine derivatives from 6-methyl-2-thiouracil and 1-acyl-2-bromoacetylenes. X-ray structural study of 3-benzoyl-7-methyl-5H-thiazolo[3,2-a]pyrimidin-5-one

被引：6

作者：

Elokhina, VN ^{[1
]}

Nakhmanovich, AS ^{[1
]}

Stepanova, ZV ^{[1
]}

Lopyrev, VA ^{[1
]}

Bannikova, OB ^{[1
]}

Struchkov, YT ^{[1
]}

Shishkin, OV ^{[1
]}

机构：

[1] RUSSIAN ACAD SCI,AN NESMEYANOV ORGANOELEMENT CPDS INST,MOSCOW 117813,RUSSIA

来源：

RUSSIAN CHEMICAL BULLETIN | 1996年 / 45卷 / 09期

关键词：

1-acyl-2-bromoacetylenes; 3-acyl-7-methyl-5H-thiazolo[3,2-a]pyrimidin-5-ones; intramolecular cyclization; X-ray structural analysis;

D O I：

10.1007/BF01430737

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

3-Acyl-7-methyl-5H-thiazolo[3,2-a]pyrimidin-5-ones were synthesized by the reaction of 1-acyl-2-bromoacetylenes with 6-methyl-2-thiouracil, carried out with heating in DMF, dioxane, or acetonitrile in the presence of triethylamine. The structure of 3-benzoyl-7-methyl-5H-thiazolo[3,2-a]pyrimidin-5-one was established by X-ray structural analysis.

引用

页码：2189 / 2191

页数：3

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