Novel therapies, for multiple myeloma

被引：5

作者：

Ryoo, JJ

Cole, CE

Anderson, KC

机构：

[1] Harvard Univ, Sch Med, Cambridge, MA 02138 USA

[2] Univ Michigan, Med Ctr, Ann Arbor, MI 48109 USA

[3] Dana Farber Canc Inst, Jerome Lipper Multiple Myeloma Ctr, Boston, MA 02115 USA

来源：

BLOOD REVIEWS | 2002年 / 16卷 / 03期

关键词：

multiple myeloma; proteasome inhibitors; thalidomide; immunomodulatory drugs; arsenic trioxide; angiogenesis; cytokines;

D O I：

10.1016/S0268-960X(02)00009-7

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Multiple myeloma (MM) continues to evade cure by conventional therapies, increasing the urgency for new, biologically based treatments. Reviewed in this discussion are novel chemotherapies under clinical trial that capitalize upon greater comprehension of tumor pathophysiology. In targeting tumor biology, these therapies serve. as a model of treatment with great potential for improving outcomes in patients with MM. (C) 2002 Elsevier Science Ltd. All rights reserved.

引用

页码：167 / 174

页数：8

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