Simultaneous determination of important alkaloids in Papaver somniferum using reversed phase high performance liquid chromatography

被引：26

作者：

Singh, DV ^{[1
]}

Prajapati, S ^{[1
]}

Bajpai, S ^{[1
]}

Verma, RK ^{[1
]}

Gupta, MM ^{[1
]}

Kumar, S ^{[1
]}

机构：

[1] Cent Inst Med & Aromat Plants, Lucknow 226015, Uttar Pradesh, India

来源：

JOURNAL OF LIQUID CHROMATOGRAPHY & RELATED TECHNOLOGIES | 2000年 / 23卷 / 11期

关键词：

D O I：

10.1081/JLC-100100450

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

A simple and rapid method for the quantitation of eight pharmacologically important drugs, morphine (1), codeine (2), oripavine (3), codeinone (4), reticuline (5), thebaine (6), papaverine (7), and narcotine (8), in Papaver somniferum samples by reversed phase liquid chromatography with photodiode array detection is described. The separation of these compounds was performed with acetonitrile-phosphate buffer (pH maintained to 3.8 using acetic acid) ( 20 : 80) using a Durasil C-18 column with 10-mu m particles (250 mm x 4.6 mm I.D.).

引用

页码：1757 / 1764

页数：8

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