Cytokines and the gut

被引：16

作者：

McAlindon, ME ^{[1
]}

Mahida, YR ^{[1
]}

机构：

[1] UNIV NOTTINGHAM HOSP, QUEENS MED CTR, DIV GASTROENTEROL, NOTTINGHAM NG7 2UH, ENGLAND

来源：

EUROPEAN JOURNAL OF GASTROENTEROLOGY & HEPATOLOGY | 1997年 / 9卷 / 11期

关键词：

cytokines; interleukins; macrophage; Salmonella spp; Shigella spp; Helicobacter pylori; Clostridium difficile; ulcerative colitis; Crohn's disease; coeliac disease;

D O I：

10.1097/00042737-199711000-00004

中图分类号：

R57 [消化系及腹部疾病];

学科分类号：

摘要：

Cytokines are peptide regulatory factors which are involved in initiating, amplifying, perpetuating and resolving the immune and inflammatory responses. Each may have several actions, but can be broadly categorized into pro-and anti-inflammatory cytokines. The cytokine profile depends on the nature of the antigen, how it is presented to the host, and which cell types are involved in the response. Elucidation of the cytokine cascade will improve understanding of the mechanisms of inflammation, and may allow the identification of therapeutic targets in chronic inflammatory diseases of unknown aetiology.

引用

页码：1045 / 1050

页数：6

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