Epoxy-based monoliths. A novel hydrophilic separation material for liquid chromatography of biomolecules

被引：61

作者：

Nguyen, Anh Mai ^{[1
]}

Irgum, Knut ^{[1
]}

机构：

[1] Umea Univ, Dept Chem, S-90187 Umea, Sweden

来源：

CHEMISTRY OF MATERIALS | 2006年 / 18卷 / 26期

关键词：

D O I：

10.1021/cm060645j

中图分类号：

O64 [物理化学（理论化学）、化学物理学];

学科分类号：

070304 ; 081704 ;

摘要：

In our efforts to develop novel hydrophilic monolithic porous materials for use as supports in liquid chromatographic separation of proteins, polymers based on epoxy monomers and diamines as curing agents were synthesized. The epoxy dispersed phase was emulsified in an aqueous phase containing the amine with the aid of a nonionic polymeric surfactant, and the resulting emulsions were thermally polymerized. Various factors, namely, the type of epoxy component, levels of reactants, type and concentration of diluents, and curing procedures, were studied to obtain suitable morphology and adequate mechanical properties for their intended use. Characterization of their morphologies and porous properties was done using scanning electron microscopy, nitrogen adsorption/desorption measurement (BET method), mercury intrusion porosimetry, and X-ray photoelectron spectroscopy.

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页码：6308 / 6315

页数：8

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