Biotransformation of cadinane sesquiterpenes by Beauveria bassiana ATCC 7159

被引：32

作者：

Buchanan, GO ^{[1
]}

Williams, LAD ^{[1
]}

Reese, PB ^{[1
]}

机构：

[1] Univ W Indies, Dept Chem, Kingston 7, Jamaica

来源：

PHYTOCHEMISTRY | 2000年 / 54卷 / 01期

关键词：

Beauveria bassiana ATCC 7159; deuteromycotina; biotransformation; cadinane; sesquiterpene; Hyptis verticillata;

D O I：

10.1016/S0031-9422(00)00024-8

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Incubation of cadina-4.10(15)-dien-3-one with Beauveria bassiana ATCC 7159 has resulted in the production of nine novel sesquiterpenes. These metabolites were identified as (4S)-cadin-10(15)-en-3-one, (4S)-3 alpha-hydroxycadin-10(15)-ene, (4R)-3 alpha-hydloxycadin-10(15)-ene, (4S)-3 beta-hydroxycadin-10(15)-ene, (4S)-3 beta-hydroxycadina-10(15),12(14)-diene, (4S)-13-hydroxycadin-10(15)-en-3-one, (4S)-12-hydroxycadin-10(15)-en-3-one, (4R)-3 beta,14-dihydroxycadin-10(15)-ene and 3 alpha-hydroxycadina-4,10(15)diene. The allylic alcohol 3 alpha-hydroxycadina-4 10(15)-diene was also biotransformed to afford cadina-4,10(15)-dien-3-one, (4S)-cadin-10(15)-en-3-one and (4S)-12-hpdroxycadin-10(15)-en-3-one. The insecticidal potential and phytotoxicity of the isolated metabolites have been evaluated, (C) 2000 Elsevier Science Ltd. All rights reserved.

引用

页码：39 / 45

页数：7

共 14 条

[1] REDUCTION OF 1,1-DIDEUTERIO-2-METHYL-2-PENTEN-1-OL BY BEAUVERIA-SULFURESCENS - MECHANISM OF THE MICROBIOLOGICAL REDUCTION OF ALPHA,BETA-UNSATURATED ALDEHYDES AND ALCOHOLS [J].