Dance band on the Titanic -: Biomechanical signaling in cardiac hypertrophy

被引：81

作者：

Sussman, MA

McCulloch, A

Borg, TK ^{[1
]}

机构：

[1] Univ S Carolina, Dept Anat & Dev Biol, Columbia, SC 29208 USA

[2] Childrens Hosp Res Fdn, Div Mol Cardiovasc Biol, Cincinnati, OH 45229 USA

[3] Inst Mol Med, Dept Bioengn, La Jolla, CA USA

来源：

CIRCULATION RESEARCH | 2002年 / 91卷 / 10期

关键词：

mechanical signaling; cardiac hypertrophy; extracellular matrix;

D O I：

10.1161/01.RES.0000041680.43270.F8

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Biomechanical signaling is a complex interaction of both intracellular and extracellular components. Both passive and active components are involved in the extracellular environment to signal through specific receptors to multiple signaling pathways. This review provides an overview of extracellular matrix, specific receptors, and signaling pathways for biomechanical stimulation in cardiac hypertrophy.

引用

收藏

页码：888 / 898

页数：11

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