Searching for significance in TCR-cytoskeleton interactions

被引：28

作者：

Caplan, S ^{[1
]}

Baniyash, M

机构：

[1] Inst Chil Hlth & Human Dev, Cell Biol & Metab Branch, NIH, Bethesda, MD 20892 USA

[2] Hebrew Univ Jerusalem, Hadassah Med Sch, Lautenberg Ctr Gen & Tumor Immunol, IL-91120 Jerusalem, Israel

来源：

IMMUNOLOGY TODAY | 2000年 / 21卷 / 05期

关键词：

D O I：

10.1016/S0167-5699(00)01604-2

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Two T-cell receptor (TCR) populations are expressed on T cells; one is linked to the cytoskeleton via its zeta chain. These cytoskeleton-linked receptors (30-40% of the total number of TCRs) might be important in TCR-mediated signaling and/or concurrent events. Here, differences between the two populations are summarized, and new data are examined to speculate on the functional significance of cytoskeleton-linked TCRs.

引用

页码：223 / 228

页数：6

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