Single-DNA Molecule Nanomotor Regulated by Photons

被引：88

作者：

Kang, Huaizhi ^{[1
,2
,3
]}

Liu, Haipeng ^{[1
,2
,3
]}

Phillips, Joseph A. ^{[1
,2
,3
]}

Cao, Zehui ^{[1
,2
,3
]}

Kim, Youngmi ^{[1
,2
,3
]}

Chen, Yan ^{[1
,2
,3
]}

Yang, Zunyi ^{[4
]}

Li, Jianwei ^{[1
,2
,3
]}

Tan, Weihong ^{[1
,2
,3
]}

机构：

[1] Univ Florida, Ctr Res Bio Nano Interface, Dept Chem, Gainesville, FL 32611 USA

[2] Univ Florida, Dept Physiol & Funct Genom, Shands Canc Ctr, UF Genet Inst, Gainesville, FL 32611 USA

[3] Univ Florida, McKnight Brain Inst, Gainesville, FL 32611 USA

[4] Fdn Appl Mol Evolut, Gainesville, FL 32601 USA

来源：

NANO LETTERS | 2009年 / 9卷 / 07期

关键词：

TRIPLEX FORMATION; DUPLEX FORMATION; STRANDED-DNA; AZOBENZENE; PHOTOREGULATION; DESIGN; OCTAHEDRON; WALKER; DEVICE; TRACK;

D O I：

10.1021/nl9011694

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

We report the design of a single-molecule nanomotor driven by photons. The nanomotor is a DNA hairpin-structured molecule incorporated with azobenzene moieties to facilitate reversible photocontrollable switching. Upon repeated UV-vis irradiation, this nanomotor displayed 40-50% open-close conversion efficiency. This type of nanomotor displays well-regulated responses and can be operated under mild conditions with no output of waste. In contrast to multiple-component DNA nanomachines, the intramolecular interaction in this single-molecule system offers unique concentration-independent motor functionality. Moreover, the hairpin structure of the motor backbone can significantly improve the efficiency of light-to-movement energy conversion. These results suggest that azobenzene-incorporated, hairpin-structured single-molecule DNA nanomotors have promising potential for applications which require highly efficient light-driven molecular motors.

引用

页码：2690 / 2696

页数：7

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