Temporal decline in the prognostic impact of a recurrent acute myocardial infarction 1985 to 2002

被引:43
作者
Buch, P.
Rasmussen, S.
Gislason, G. H.
Rasmussen, J. N.
Kober, L.
Gadsboll, N.
Stender, S.
Madsen, M.
Torp-Pedersen, C.
Abildstrom, S. Z.
机构
[1] Bispebjerg Hosp, Dept Cardiovasc Med, DK-2400 Copenhagen NV, Denmark
[2] Natl Inst Publ Hlth, DK-1399 Copenhagen K, Denmark
[3] Gentofte Univ Hosp, Dept Cardiol, DK-2900 Hellerup, Denmark
[4] Copenhagen Univ Hosp, Rigshosp, Heart Ctr, Dept Cardiol, DK-2100 Copenhagen, Denmark
[5] Roskilde Cty Hosp, Dept Med, DK-4000 Roskilde, Denmark
关键词
D O I
10.1136/hrt.2006.092213
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Objective: To investigate trends in case-fatality and prognostic impact from recurrent acute myocardial infarction (re-AMI) during 1985-2002. Design: Retrospective cohort study using nationwide administrative data from Denmark. Settings: National registries on hospital admissions and causes of death were linked to identify patients with first AMI, re-AMI and subsequent prognosis. Patients: Patients >= 30 years old with a discharge diagnosis of AMI during 1985 - 2002 were tracked for first hospital admission for re-AMI 1 year after discharge. Main outcome measures: One-year case-fatality. Results: 166 472 patients were identified with a first AMI; 14 123 developed re-AMI. One-year crude casefatality from first AMI/re-AMI was 39% versus 43% in 1985 - 1989 and 25% versus 29% in 2000 - 2002, respectively. In 1985 - 89, 35 795 patients survived to discharge (71%); of these 2.5% experienced reinfarction within 30 days (early reinfarction) and an additional 9.0% reinfarction within days 31 - 365 (late re-AMI). Re-AMI carried a poor prognosis in 1985 - 1989 compared to no re-AMI with age- and sex-adjusted relative risk of 1-year case-fatality of 7.5 (95% CI: 6.9 to 8.5) from early re-AMI and 11.7 (95% CI: 11.0 to 12.4) from late re-AMI. In 2000 - 2002, 23 552 patients (86%) survived to discharge; 4.4% had early re-AMI and 6.6% late re-AMI. Adjusted relative risk of 1-year case-fatality had declined to 2.1 (95% CI: 1.9 to 2.5) from early re-AMI and 5.6 (95% CI: 5.1 to 6.2) from late re-AMI compared to patients without reinfarction. Conclusion: Prognosis after AMI has improved substantially during the latest two decades and extends to patients with re-AMI.
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页码:210 / 215
页数:6
相关论文
共 30 条
[1]   A comparison of coronary angioplasty with fibrinolytic therapy in acute myocardial infarction [J].
Andersen, HR ;
Nielsen, TT ;
Rasmussen, K ;
Thuesen, L ;
Kelbaek, H ;
Thayssen, P ;
Abildgaard, U ;
Pedersen, F ;
Madsen, JK ;
Grande, P ;
Villadsen, AB ;
Krusell, LR ;
Haghfelt, T ;
Lomholt, P ;
Husted, SE ;
Vigholt, E ;
Kjaergard, HK ;
Mortensen, LS .
NEW ENGLAND JOURNAL OF MEDICINE, 2003, 349 (08) :733-742
[2]  
Andersen TF, 1999, DAN MED BULL, V46, P263
[3]  
[Anonymous], [No title captured], DOI 10.1053/eurj.2000.2305
[4]   PROGNOSTIC-SIGNIFICANCE OF NONFATAL MYOCARDIAL REINFARCTION [J].
BENHORIN, J ;
MOSS, AJ ;
OAKES, D .
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 1990, 15 (02) :253-258
[5]   Trends in case-fatality in 117 718 patients admitted with acute myocardial infarction in Scotland [J].
Capewell, S ;
Livingston, BM ;
MacIntyre, K ;
Chalmers, JWT ;
Boyd, J ;
Finlayson, A ;
Redpath, A ;
Pell, JP ;
Evans, CJ ;
McMurray, JJV .
EUROPEAN HEART JOURNAL, 2000, 21 (22) :1833-1840
[6]   Predictors of and outcomes of early thrombosis following balloon angioplasty versus primary stenting in acute myocardial infarction and usefulness of abciximab (The CADILLAC trial) [J].
Dangas, G ;
Aymong, ED ;
Mehran, R ;
Tcheng, JE ;
Grines, CL ;
Cox, DA ;
Garcia, E ;
Griffin, JJ ;
Guagliumi, G ;
Stuckey, T ;
Lansky, AJ ;
Stone, GW .
AMERICAN JOURNAL OF CARDIOLOGY, 2004, 94 (08) :983-988
[7]   NONFATAL CARDIAC EVENTS AND RECURRENT INFARCTION IN THE YEAR AFTER ACUTE MYOCARDIAL-INFARCTION [J].
DWYER, EM ;
MCMASTER, P ;
GREENBERG, H .
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 1984, 4 (04) :695-702
[8]   Routine invasive strategy within 24 hours of thrombolysis versus ischaemia-guided conservative approach for acute myocardial infarction with ST-segment elevation (GRACIA-1):: a randomised controlled trial [J].
Fernandez-Avilés, F ;
Alonso, JJ ;
Castro-Beiras, A ;
Vázquez, N ;
Blanco, J ;
Alonso-Briales, J ;
López-Mesa, J ;
Fernández-Vazquez, F ;
Calvo, I ;
Martínez-Elbal, L ;
San Román, JA ;
Ramos, B .
LANCET, 2004, 364 (9439) :1045-1053
[9]   Early and long-term clinical outcomes associated with reinfarction following fibrinolytic administration in the thrombolysis in myocardial infarction trials [J].
Gibson, CM ;
Karha, J ;
Murphy, SA ;
James, D ;
Morrow, DA ;
Cannon, CP ;
Glugliano, RP ;
Antman, EM ;
Braunwald, E .
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 2003, 42 (01) :7-16
[10]   FACTORS ASSOCIATED WITH RECURRENT MYOCARDIAL-INFARCTION WITHIN ONE YEAR AFTER ACUTE MYOCARDIAL-INFARCTION [J].
GILPIN, E ;
RICOU, F ;
DITTRICH, H ;
NICOD, P ;
HENNING, H ;
ROSS, J .
AMERICAN HEART JOURNAL, 1991, 121 (02) :457-465