Pharmacologic management of insomnia: Past, present, and future

被引：47

作者：

Curry, Denise Troy

Eisenstein, Rhody D.

Walsh, James K.

机构：

[1] St Johns Mercy Med Ctr, Sleep Med & Res Ctr, Chesterfield, MO 63017 USA

[2] St Lukes Hosp, Chesterfield, MO 63017 USA

来源：

PSYCHIATRIC CLINICS OF NORTH AMERICA | 2006年 / 29卷 / 04期

关键词：

D O I：

10.1016/j.psc.2006.09.006

中图分类号：

R749 [精神病学];

学科分类号：

100205 [精神病与精神卫生学];

摘要：

Views on die etiology and morbidities associated with insomnia are evolving and affect clinicians' approach to the pharmacologic management of insomnia. Currently, benzodiazepine receptor agonists (BzRAs) and a single melatonin receptor agonist are recognized as safe and efficacious hypnotics. Variability in BzRAs, pharmacokinetics, and manipulation of dose provide clinicians with options that meet the needs of most patients. Other drugs (eg, sedating antidepressants) also are used commonly *in clinical practice to treat insomnia, but evidence is lacking to support this most cases. Improvement in managing insomnia will result from systematic research with these drugs, with drugs in development, and with novel uses, such as cotherapy.

引用

页码：871 / +

页数：25

共 100 条

[1]

Agargun MY, 1997, J CLIN PSYCHIAT, V58, P249

[2]

[Anonymous], 2005, SLEEP, V28, P1049

[3]

Insomnia and hypnotic use, recorded in the minimum data set, as predictors of falls and hip fractures in michigan nursing homes [J].