Efficient synthesis of enantiomerically pure C-2-symmetric diols via the allylboration of appropriate dialdehydes

被引：69

作者：

Ramachandran, PV ^{[1
]}

Chen, GM ^{[1
]}

Brown, HC ^{[1
]}

机构：

[1] PURDUE UNIV, HC BROWN & RB WETHERILL LABS CHEM, W LAFAYETTE, IN 47907 USA

来源：

TETRAHEDRON LETTERS | 1997年 / 38卷 / 14期

关键词：

D O I：

10.1016/S0040-4039(97)00414-0

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The reaction of the enantiomers of B-allyidiisopinocampheylborane with 1,2-, 1,3-, and 1,4-benzenedialdehydes, 2,6-pyridinedicarboxaldehyde, glyoxal, and glutaric dialdehyde, provides the corresponding enantiomers of the bis-homoallylic alcohols in 88-98% de, and greater than or equal to 98% ee. (C) 1997 Elsevier Science Ltd.

引用

页码：2417 / 2420

页数：4

共 19 条

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