Effect of genotype on behavioral and hormonal components of sexual activation of male mice

被引：6

作者：

Amstislavskaya, TG ^{[1
]}

Khrapova, MV ^{[1
]}

机构：

[1] Russian Acad Sci, Inst Cytol & Genet, Lab Behav Phenogenet, Siberian Branch, Novosibirsk 630090, Russia

来源：

BULLETIN OF EXPERIMENTAL BIOLOGY AND MEDICINE | 2002年 / 133卷 / 05期

关键词：

mice; sexual activation; testosterone; genotype; genetic control;

D O I：

10.1023/A:1019865822028

中图分类号：

R-3 [医学研究方法]; R3 [基础医学];

学科分类号：

1001 ;

摘要：

Possible relationship between changes in behavior and hormone response to a sex stimulus was studied by comparing these parameters in mice of 10 genotypes. All males spent more time near the wall during the very first 5 min after appearance of the female. Strains with the minimum (DBA/2, C57B1/6J) and maximum (SWR, CBA) time spent near the wall were distinguished. Genotypical differences in hormone response during sexual activation were detected. Considerable increase in testosterone concentration in the peripheral blood was observed in male's of 6 of the 10 mouse strains 30 min after appearance of the female. Mouse strains with contrast sexual activation were distinguished. No correlation between behavioral and hormonal response was detected. The detected genetically determined variability of the behavioral and hormonal components of sexual activation is determined by hereditary peculiarities of central mechanisms regulating the studied functions.

引用

页码：475 / 477

页数：3

共 8 条

[1]

AMSTISLAVSKAYA T G, 1989, Problemy Endokria, V35, P63

[2] INCREASED SENSITIVITY OF SEMINAL-VESICLES TO TESTOSTERONE IN A MOUSE STRAIN WITH LOW PLASMA TESTOSTERONE LEVELS [J].