Amyloid immunotherapy-engendered CNS inflammation

被引:8
作者
Bowers, WJ
Federoff, HJ
机构
[1] Univ Rochester, Sch Med & Dent, Dept Neurol, Rochester, NY 14642 USA
[2] Univ Rochester, Sch Med & Dent, Dept Microbiol, Rochester, NY 14642 USA
[3] Univ Rochester, Sch Med & Dent, Dept Immunol, Rochester, NY 14642 USA
[4] Univ Rochester, Sch Med & Dent, Ctr Aging & Dev Biol, Rochester, NY 14642 USA
关键词
D O I
10.1016/S0197-4580(02)00035-0
中图分类号
R592 [老年病学]; C [社会科学总论];
学科分类号
03 ; 0303 ; 100203 ;
摘要
引用
收藏
页码:675 / 676
页数:2
相关论文
共 7 条
[1]   Genetic dissection of Alzheimer's disease and related dementias: Amyloid and its relationship to tau [J].
Hardy, J ;
Duff, K ;
Hardy, KG ;
Perez-Tur, J ;
Hutton, M .
NATURE NEUROSCIENCE, 1998, 1 (05) :355-358
[2]   Aβ peptide immunization reduces behavioural impairment and plaques in a model of Alzheimer's disease [J].
Janus, C ;
Pearson, J ;
McLaurin, J ;
Mathews, PM ;
Jiang, Y ;
Schmidt, SD ;
Chishti, MA ;
Horne, P ;
Heslin, D ;
French, J ;
Mount, HTJ ;
Nixon, RA ;
Mercken, M ;
Bergeron, C ;
Fraser, PE ;
St George-Hyslop, P ;
Westaway, D .
NATURE, 2000, 408 (6815) :979-982
[3]   Diffusible, nonfibrillar ligands derived from Aβ1-42 are potent central nervous system neurotoxins [J].
Lambert, MP ;
Barlow, AK ;
Chromy, BA ;
Edwards, C ;
Freed, R ;
Liosatos, M ;
Morgan, TE ;
Rozovsky, I ;
Trommer, B ;
Viola, KL ;
Wals, P ;
Zhang, C ;
Finch, CE ;
Krafft, GA ;
Klein, WL .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1998, 95 (11) :6448-6453
[4]  
Miravalle L, 2000, J BIOL CHEM, V275, P27110
[5]   Aβ peptide vaccination prevents memory loss in an animal model of Alzheimer's disease [J].
Morgan, D ;
Diamond, DM ;
Gottschall, PE ;
Ugen, KE ;
Dickey, C ;
Hardy, J ;
Duff, K ;
Jantzen, P ;
DiCarlo, G ;
Wilcock, D ;
Connor, K ;
Hatcher, J ;
Hope, C ;
Gordon, M ;
Arendash, GW .
NATURE, 2000, 408 (6815) :982-985
[6]   Immunization with amyloid-β attenuates Alzheimer disease-like pathology in the PDAPP mouse [J].
Schenk, D ;
Barbour, R ;
Dunn, W ;
Gordon, G ;
Grajeda, H ;
Guido, T ;
Hu, K ;
Huang, JP ;
Johnson-Wood, K ;
Khan, K ;
Kholodenko, D ;
Lee, M ;
Liao, ZM ;
Lieberburg, I ;
Motter, R ;
Mutter, L ;
Soriano, F ;
Shopp, G ;
Vasquez, N ;
Vandevert, C ;
Walker, S ;
Wogulis, M ;
Yednock, T ;
Games, D ;
Seubert, P .
NATURE, 1999, 400 (6740) :173-177
[7]   Rapid tyrosine phosphorylation of neuronal proteins including tau and focal adhesion kinase in response to amyloid-β peptide exposure:: Involvement of src family protein kinases [J].
Williamson, R ;
Scales, T ;
Clark, BR ;
Gibb, G ;
Reynolds, CH ;
Kellie, S ;
Bird, IN ;
Varndell, IM ;
Sheppard, PW ;
Everall, I ;
Anderton, BH .
JOURNAL OF NEUROSCIENCE, 2002, 22 (01) :10-20