Evaluation of the BDProbeTec™ ET DTB assay for direct detection of Mycobacterium tuberculosis complex from clinical samples

被引：19

作者：

Maugein, J ^{[1
]}

Fourche, J ^{[1
]}

Vacher, S ^{[1
]}

Grimond, C ^{[1
]}

Bebear, C ^{[1
]}

机构：

[1] Hop Haut Leveque, Bacteriol Lab, F-33604 Pessac, France

来源：

DIAGNOSTIC MICROBIOLOGY AND INFECTIOUS DISEASE | 2002年 / 44卷 / 02期

关键词：

D O I：

10.1016/S0732-8893(02)00427-3

中图分类号：

R51 [传染病];

学科分类号：

100401 ;

摘要：

The purpose of this study was to evaluate the ability of BDProbeTeC(Tm) ET DTB system to detect Mycobacterium tuberculosis complex directly from clinical specimens. A total of 628 specimens (553 respiratory and 75 non respiratory specimens) were collected from 478 patients. These samples were tested with the BDProbeTec(Tm) ET DTB assay and results were compared with acid fast microscopy and culture. Sixty eight out of 77 culture positive M. tuberculosis complex samples were detected with overall sensitivity and specificity of 89.5% and 98.2% respectively. Overall sensitivity was 100% in smear positive samples and 79% in smear negative samples. After resolution of discrepant results, sensitivity and specificity for respiratory samples were 91.6% and 98.7% respectively. BDProbeTec(Tm) ET DTB assay demonstrated to be a rapid, sensitive and specific method for detection of M. tuberculosis complex. (C) 2002 Elsevier Science Inc. All rights reserved.

引用

页码：151 / 155

页数：5

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