Left ventricular diastolic dysfunction of the cardiac surgery patient; a point of view for the cardiac surgeon and cardio-anesthesiologist

被引:30
作者
Apostolakis, Efstratios E. [1 ]
Baikoussis, Nikolaos G. [1 ,2 ]
Parissis, Haralabos [3 ]
Siminelakis, Stavros N. [2 ]
Papadopoulos, Georgios S. [4 ,5 ]
机构
[1] Univ Patras, Sch Med, Dept Cardiothorac Surg, GR-26110 Patras, Greece
[2] Univ Ioannina, Sch Med, Dept Cardiac Surg, GR-45110 Ioannina, Greece
[3] Basildon & Thurrock Univ Hosp NHS FT, Basildon, Essex, England
[4] Univ Ioannina, Sch Med, Dept Clin Anesthesiol, GR-45110 Ioannina, Greece
[5] Univ Ioannina, Sch Med, Intens Postoperat Care Unit, GR-45110 Ioannina, Greece
关键词
ARTERY-BYPASS GRAFT; BRAIN NATRIURETIC PEPTIDE; HEART-FAILURE; DOPPLER-ECHOCARDIOGRAPHY; ON-PUMP; MYOCARDIAL-FUNCTION; SYSTOLIC FUNCTION; FILLING PRESSURE; VELOCITY; HYPERTENSION;
D O I
10.1186/1749-8090-4-67
中图分类号
R5 [内科学];
学科分类号
100201 [内科学];
摘要
Background: Left ventricular diastolic dysfunction (DD) is defined as the inability of the ventricle to fill to a normal end-diastolic volume, both during exercise as well as at rest, while left atrial pressure does not exceed 12 mm Hg. We examined the concept of left ventricular diastolic dysfunction in a cardiac surgery setting. Materials and methods: Literature review was carried out in order to identify the overall experience of an important and highly underestimated issue: the unexpected adverse outcome due to ventricular stiffness, following cardiac surgery. Results: Although diverse group of patients for cardiac surgery could potentially affected from diastolic dysfunction, there are only few studies looking in to the impact of DD on the postoperative outcome; Trans-thoracic echo-cardiography (TTE) is the main stay for the diagnosis of DD. Intraoperative trans-oesophageal (TOE) adds to the management. Subgroups of DD can be defined with prognostic significance. Conclusion: DD with elevated left ventricular end-diastolic pressure can predispose to increased perioperative mortality and morbidity. Furthermore, DD is often associated with systolic dysfunction, left ventricular hypertrophy or indeed pulmonary hypertension. When the diagnosis of DD is made, peri-operative attention to this group of patients becomes mandatory.
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页数:10
相关论文
共 83 条
[1]
Right ventricular function before and after an uncomplicated coronary artery bypass graft as assessed by pulsed wave Doppler tissue imaging of the tricuspid annulus [J].
Alam, M ;
Hedman, A ;
Nordlander, R ;
Samad, B .
AMERICAN HEART JOURNAL, 2003, 146 (03) :520-526
[2]
Evaluation and management of diastolic heart failure [J].
Angeja, BG ;
Grossman, W .
CIRCULATION, 2003, 107 (05) :659-663
[3]
Isolated systolic hypertension is associated with adverse outcomes from coronary artery bypass grafting surgery [J].
Aronson, S ;
Boisvert, D ;
Lapp, W .
ANESTHESIA AND ANALGESIA, 2002, 94 (05) :1079-1084
[4]
Diastolic dysfunction is predictive of difficult weaning from cardiopulmonary bypass [J].
Bernard, F ;
Denault, A ;
Babin, D ;
Goyer, C ;
Couture, P ;
Couturier, A ;
Buithieu, J .
ANESTHESIA AND ANALGESIA, 2001, 92 (02) :291-298
[5]
LEFT-VENTRICULAR DIASTOLIC DYSFUNCTION AS A CAUSE OF CONGESTIVE-HEART-FAILURE - MECHANISMS AND MANAGEMENT [J].
BONOW, RO ;
UDELSON, JE .
ANNALS OF INTERNAL MEDICINE, 1992, 117 (06) :502-510
[6]
Braunwald E, 2001, HEART DIS, P451
[7]
BRISTOW M, 2005, BRAUNWALDS HEART DIS, P610
[8]
Tei-Index in patients with mild-to-moderate congestive heart failure [J].
Bruch, C ;
Schmermund, A ;
Marin, D ;
Katz, M ;
Bartel, T ;
Schaar, J ;
Erbel, R .
EUROPEAN HEART JOURNAL, 2000, 21 (22) :1888-1895
[9]
Human SERCA2a levels correlate inversely with age in senescent human myocardium [J].
Cain, BS ;
Meldrum, DR ;
Joo, KS ;
Wang, JF ;
Meng, XZ ;
Cleveland, JC ;
Banerjee, A ;
Harken, AH .
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 1998, 32 (02) :458-467
[10]
Diastolic dysfunction in stunned myocardium:: a state of abnormal excitation-con traction coupling that is limited by Na+-H+ exchange inhibition [J].
Castella, Manuel ;
Buckberg, Gerald D. ;
Saleh, Saleh .
EUROPEAN JOURNAL OF CARDIO-THORACIC SURGERY, 2006, 29 :S107-S114