Analysis of EEG data from weak-field magnetic stimulation of mesial temporal lobe epilepsy patients

被引：22

作者：

Dobson, J

St Pierre, TG

Schultheiss-Grassi, PP

Wieser, HG

Kuster, N

机构：

[1] Keele Univ, Ctr Sci & Technol Med, Stoke On Trent ST4 7QB, Staffs, England

[2] Univ Western Australia, Dept Phys, Biophys Programme, Nedlands, WA 6907, Australia

[3] Sun Microsyst Inc, CH-8005 Zurich, Switzerland

[4] Univ Zurich Hosp, Neurol Clin, Dept EEG & Epileptol, CH-8091 Zurich, Switzerland

[5] Swiss Fed Inst Technol, Swiss Fed Inst Technol, Lab EMF & Microwave Elect, CH-8092 Zurich, Switzerland

来源：

BRAIN RESEARCH | 2000年 / 868卷 / 02期

关键词：

magnetic stimulation; epilepsy; hippocampus; epileptiform activity; transcranial magnetic stimulation;

D O I：

10.1016/S0006-8993(00)02422-7

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

Ten patients suffering from mesial temporal lobe epilepsy were exposed to weak, DC magnetic field stimulation following computer-controlled protocols established in previous studies. Poisson statistical analysis of the ten patients undergoing semi-invasive (foramen ovale) electrode monitoring reveals that for at least one experimental protocol, application of DC magnetic fields alters interictal epileptiform spike activity in five of ten patients. Similar results also have been observed in the analysis of both human and rat brains by employing weak, alternating magnetic field stimulation. Further study is necessary in order to optimize the magnetic field exposure protocol. (C) 2000 Elsevier Science B.V. All rights reserved.

引用

页码：386 / 391

页数：6

共 12 条

[1] ELECTRICAL STATES IN THE RABBIT BRAIN CAN BE ALTERED BY LIGHT AND ELECTROMAGNETIC-FIELDS [J].