Endemic carbapenem resistance associated with OXA-40 carbapenemase among Acinetobacter baumannii isolates from a hospital in northern Spain

被引:64
作者
Lopez-Otsoa, F
Gallego, L
Towner, KJ [1 ]
Tysall, L
Woodford, N
Livermore, DM
机构
[1] Univ Nottingham Hosp, Queens Med Ctr, Publ Hlth Lab, Mol Diagnost & Typing Unit, Nottingham NG7 2UH, England
[2] Univ Basque Country, Fac Med & Odontol, Dept Microbiol Immunol & Parasitol, E-48080 Bilbao, Spain
[3] Cent Publ Hlth Lab, Antibiot Resistance Monitoring & Reference Lab, London NW9 5HT, England
关键词
D O I
10.1128/JCM.40.12.4741-4743.2002
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
Eighty-two carbapenem-resistant isolates of Acinetobacter baumannii from a single hospital in Bilbao were typed into two major clusters and several subclusters. Disk synergy tests and PCR indicated the production of a zinc-independent OXA-class carbapenemase. Sequencing identified this enzyme, OXA-40, as a variant of the OXA-24-OXA-25-OXA-26 cluster.
引用
收藏
页码:4741 / 4743
页数:3
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