Aggressive natural killer (NK) cell lymphoma: Report of a pediatric case and review of the literature

被引：23

作者：

Ohnuma, K

Toyoda, Y

Nishihira, H

Iguchi, A

Honda, K

Nagao, T

Kigasawa, H

Tanaka, Y

Kikuta, H

机构：

[1] Department of Oncology, Kanagawa Children's Medical Center, Minami ku, Yokohama, Kanagawa

[2] Department of Hematology, Kanagawa Children's Medical Center, Minami ku, Yokohama, Kanagawa

[3] Department of Blood Transfusion, Kanagawa Children's Medical Center, Minami ku, Yokohama, Kanagawa

[4] Department of Pathology, Kanagawa Children's Medical Center, Minami ku, Yokohama, Kanagawa

[5] Department of Pediatrics, Hokkaido University, School of Medicine, Sapporo, Hokkaido

来源：

LEUKEMIA & LYMPHOMA | 1997年 / 25卷 / 3-4期

关键词：

aggressive NK cell lymphoma; large granular lymphocyte; EB virus; LARGE GRANULAR LYMPHOCYTES; EPSTEIN-BARR-VIRUS; CLONAL EXPANSION; VIRAL-DNA; LEUKEMIA; ESTABLISHMENT; PHENOTYPE; LINEAGE; PATIENT;

D O I：

10.3109/10428199709114178

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

We report a rare pediatric case of aggressive natural killer (NK) cell lymphoma, characterized by acute onset hepatosplenomegaly and respiratory distress, and infiltration by large granular Lymphocytes with the phenotype of CDS-CD16-CD56+. The patient has remained in complete remission after short-pulse intensive chemotherapy, and myeloablative therapy followed by allogeneic bone marrow transplantation. We compare our case with 7 other children with NK cell leukemia reported from other institutions.

引用

页码：387 / 392

页数：6

共 27 条

[1]

FERNANDEZ LA, 1986, BLOOD, V67, P925

[2]

FUKUDA J, 1994, JPN J CLIN HEMATOL, V35, P588

[3] MULTIPLE PULMONARY NODULES MANIFESTED IN A PATIENT WITH NK CELL GRANULAR LYMPHOCYTE PROLIFERATIVE DISORDER [J].