We quantify the consequences of intergalactic dust produced by the first Type II supernovae in the universe. The fraction of gas converted into stars is calibrated based on the observed C/H ratio in the intergalactic medium at z = 3, assuming a Scale mass function for the stars. The associated dust absorbs starlight energy and emits it at longer wavelengths. For a uniform mix of metals and dust with the intergalactic gas, we find that the dust distorts the microwave background spectrum by a y-parameter in the range (0.06-6) x 10(-5) (M-SN/0.3 M.), where M-SN is the average mass of dust produced per supernova. The opacity of intergalactic dust to infrared sources at redshifts of z greater than or similar to 10 is significant, tau(dust) = (0.1-1) x (M-SN/0.3 M.), and could be detected with the Next Generation Space Telescope. Although dust suppresses the Ly alpha emission from early sources, the redshifts of star clusters at z = 10-35 can be easily inferred from the Lyman limit break in their infrared spectrum between 1 and 3.5 mu m.