Failure to detect Chlamydia trachomatis in cell culture by using a monoclonal antibody directed against the major outer membrane protein

被引：2

作者：

Boman, J ^{[1
]}

Gaydos, C ^{[1
]}

Juto, P ^{[1
]}

Wadell, G ^{[1
]}

Quinn, TC ^{[1
]}

机构：

[1] JOHNS HOPKINS UNIV,DEPT MED,BALTIMORE,MD

来源：

JOURNAL OF CLINICAL MICROBIOLOGY | 1997年 / 35卷 / 10期

关键词：

D O I：

10.1128/JCM.35.10.2679-2680.1997

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

Two commercially available monoclonal antibodies for cell culture confirmation of Chlamydia trachomatis were compared in two prospective studies and one large retrospective study. In total, more than 33,000 genital specimens were cultured in parallel and stained with both antibodies, one of which was directed against the major outer membrane protein (MOMP) and one uf which was directed against the lipopolysaccharide (LPS). We found the anti-LPS-based assay to be more sensitive and as specific as the anti-MOMP-based assay for C. trachomatis cell culture confirmation of genital specimens.

引用

页码：2679 / 2680

页数：2

共 11 条

[1]

[Anonymous], 1991, MMWR Recomm Rep, V40, P1

[2] RAPID IMMUNOTYPING OF CHLAMYDIA-TRACHOMATIS WITH MONOCLONAL-ANTIBODIES IN A SOLID-PHASE ENZYME-IMMUNOASSAY [J].