Hyperbaric oxygenation induced tolerance against focal cerebral ischemia in mice is strain dependent

被引：98

作者：

Prass, K

Wiegand, F

Schumann, P

Ahrens, M

Kapinya, K

Harms, C

Liao, WJ

Trendelenburg, G

Gertz, K

Moskowitz, MA

Knapp, F

Victorov, IV

Megow, D

Dirnagl, U ^{[1
]}

机构：

[1] Humboldt Univ, Dept Neurol, Berlin, Germany

[2] Univ Essen Gesamthsch, Dept Neurol, D-4300 Essen, Germany

[3] Univ Caen, CNRS, UMR 6551, F-14032 Caen, France

[4] Russian Acad Med Sci, Brain Res Inst, Moscow, Russia

[5] Harvard Univ, Sch Med, Massachusetts Gen Hosp, Stroke Res Lab, Charlestown, MA USA

来源：

BRAIN RESEARCH | 2000年 / 871卷 / 01期

关键词：

C57BL/6; mouse; oxygen free radical; preconditioning; SV129; stroke;

D O I：

10.1016/S0006-8993(00)02264-2

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

SV129 or C57BL/6 mice were exposed to hyperbaric oxygenation (HBO, 5 days, 1 h every day, 100% O-2 at 3 atm absolute). One day after the 5th HBO session focal cerebral ischemia was induced. In SV129 mice, HBO induced tolerance against permanent focal cerebral ischemia (n = 42, mean infarct volume reduction 27%, P = 0.001), but not against transient (30 or 60 min) focal cerebral ischemia. In the C57BL/6 strain of mice, HBO did not induce tolerance against focal cerebral ischemia, even when the duration of ischemia or the HBO protocol were modified. For the first time we demonstrate that HBO can induce tolerance to focal cerebral ischemia, but this effect is strain dependent. (C) 2000 Elsevier Science B.V. All rights reserved.

引用

收藏

页码：146 / 150

页数：5

相关论文

共 21 条

[1] Cellular distribution of the rat D-4 dopamine receptor protein in the CNS using anti-receptor antisera [J].

Ariano, MA ;

Wang, J ;

Noblett, KL ;

Larson, ER ;

Sibley, DR .

BRAIN RESEARCH, 1997, 752 (1-2) :26-34

[2] Photothrombotic middle cerebral artery occlusion in spontaneously hypertensive rats - Influence of substrain, gender, and distal middle cerebral artery patterns on infarct size [J].

Cai, H ;

Yao, H ;

Ibayashi, S ;

Uchimura, H ;

Fujishima, M .

STROKE, 1998, 29 (09) :1982-1986

[3] Adaptation to myocardial ischemia during coronary angioplasty demonstrated by clinical, electrocardiographic, echocardiographic, and metabolic parameters [J].

Eltchaninoff, H ;

Cribier, A ;

Tron, C ;

Derumeaux, G ;

Koning, R ;

Hecketsweiller, B ;

Letac, B .

AMERICAN HEART JOURNAL, 1997, 133 (04) :490-496

[4]

FARBER SA, 1995, J NEUROSCI, V15, P7442

[5] Gene-targeting studies of mammalian behavior: Is it the mutation or the background genotype? [J].

Gerlai, R .

TRENDS IN NEUROSCIENCES, 1996, 19 (05) :177-181

[6] Reduced brain edema and infarction volume in mice lacking the neuronal isoform of nitric oxide synthase after transient MCA occlusion [J].

Hara, H ;

Huang, PL ;

Panahian, N ;

Fishman, MC ;

Moskowitz, MA .

JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM, 1996, 16 (04) :605-611

[7] Differences in striatal extracellular amino acid concentrations between Wistar and Fischer 344 rats after middle cerebral artery occlusion [J].

Herz, RCG ;

Gaillard, PJ ;

deWildt, DJ ;

Versteeg, DHG .

BRAIN RESEARCH, 1996, 715 (1-2) :163-171

[8] IMMUNOHISTOCHEMICAL LOCALIZATION OF SUPEROXIDE-DISMUTASE IN THE HIPPOCAMPUS FOLLOWING ISCHEMIA IN A GERBIL MODEL OF ISCHEMIC TOLERANCE [J].

KATO, H ;

KOGURE, K ;

ARAKI, T ;

LIU, XH ;

KATO, K ;

ITOYAMA, Y .

JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM, 1995, 15 (01) :60-70

[9] Cerebral ischemia after bilateral carotid artery occlusion and intraluminal suture occlusion in mice: Evaluation of the patency of the posterior communicating artery [J].

Kitagawa, K ;

Matsumoto, M ;

Yang, GM ;

Mabuchi, T ;

Yagita, Y ;

Hori, M ;

Yanagihara, T .

JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM, 1998, 18 (05) :570-579

[10]

Kitagawa K, 1999, J NEUROSCI RES, V55, P643, DOI 10.1002/(SICI)1097-4547(19990301)55:5<643::AID-JNR11>3.0.CO