The role of the vascular endothelium in inflammatory syndromes, atherogenesis, and the propagation of disease

被引：22

作者：

Hill, GE

Whitten, CW

机构：

[1] UNIV TEXAS,SW MED CTR,DEPT ANESTHESIOL & PAIN MANAGEMENT,DALLAS,TX 75235

[2] UNIV NEBRASKA,MED CTR,DEPT ANESTHESIOL,DIV PULM & CRIT CARE MED,OMAHA,NE 68198

[3] UNIV NEBRASKA,MED CTR,DEPT INTERNAL MED,DIV PULM & CRIT CARE MED,OMAHA,NE 68198

来源：

JOURNAL OF CARDIOTHORACIC AND VASCULAR ANESTHESIA | 1997年 / 11卷 / 03期

关键词：

vascular endothelium; inflammation; adhesion molecules; nitric oxide; atherogenesis; PLATELET-ACTIVATING FACTOR; NITRIC-OXIDE SYNTHASE; CARDIOPULMONARY BYPASS; LEUKOCYTE ADHESION; REPERFUSION INJURY; PLASMINOGEN-ACTIVATOR; PROTEIN-C; MYOCARDIAL-ISCHEMIA; CELLS; SYSTEM;

D O I：

10.1016/S1053-0770(97)90101-4

中图分类号：

R614 [麻醉学];

学科分类号：

100217 ;

摘要：

The vascular endothelium is intimately involved in a wide variety of normal physiological processes, including coagulation/anticoagulation. the maintenance of vascular tone, and pathological processes, including reperfusion injury, inflammatory syndromes, and tumor cell metastasis. This review discusses the importance of increased adhesive molecule expression on the endothelial surface in promoting circulating inflammatory cell-endothelial adherence in inflammatory conditions, as well as the role of the vascular endothelium in reperfusion injury, altered microvascular permeability states, and atherogenesis. Copyright (C) 1997 by W.B. Saunders Company.

引用

页码：316 / 321

页数：6

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