Individual radiation therapy patient whole-body phantoms for peripheral dose evaluations: method and specific software

被引:16
作者
Alziar, I. [1 ,2 ,3 ,4 ]
Bonniaud, G. [4 ]
Couanet, D. [4 ]
Ruaud, J. B. [5 ]
Vicente, C. [1 ,2 ,3 ,4 ]
Giordana, G. [1 ,2 ,3 ,4 ]
Ben-Harrath, O. [1 ,2 ,3 ,4 ]
Diaz, J. C. [5 ]
Grandjean, P. [5 ]
Kafrouni, H. [5 ]
Chavaudra, J. [4 ]
Lefkopoulos, D. [4 ]
de Vathaire, F. [1 ,2 ,3 ,4 ]
Diallo, I. [1 ,2 ,3 ,4 ]
机构
[1] INSERM, U605, Villejuif, France
[2] IFR69, Villejuif, France
[3] Univ Paris 11, Villejuif, France
[4] Inst Gustave Roussy, Villejuif, France
[5] DOSIsoft, Cachan, France
关键词
PROTECTION DOSIMETRY; RADIOTHERAPY; VOLUME; CHILDHOOD; EXPOSURES; CANCER; RISK; ICTA;
D O I
10.1088/0031-9155/54/17/N01
中图分类号
R318 [生物医学工程];
学科分类号
0831 ;
摘要
This study presents a method aimed at creating radiotherapy (RT) patient-adjustable whole-body phantoms to permit retrospective and prospective peripheral dose evaluations for enhanced patient radioprotection. Our strategy involves virtual whole-body patient models (WBPM) in different RT treatment positions for both genders and for different age groups. It includes a software tool designed to match the anatomy of the phantoms with the anatomy of the actual patients, based on the quality of patient data available. The procedure for adjusting a WBPM to patient morphology includes typical dimensions available in basic auxological tables for the French population. Adjustment is semi-automatic. Because of the complexity of the human anatomy, skilled personnel are required to validate changes made in the phantom anatomy. This research is part of a global project aimed at proposing appropriate methods and software tools capable of reconstituting the anatomy and dose evaluations in the entire body of RT patients in an adapted treatment planning system (TPS). The graphic user interface is that of a TPS adapted to obtain a comfortable working process. Such WBPM have been used to supplement patient therapy planning images, usually restricted to regions involved in treatment. Here we report, as an example, the case of a patient treated for prostate cancer whose therapy planning images were complemented by an anatomy model. Although present results are preliminary and our research is ongoing, they appear encouraging, since such patient-adjusted phantoms are crucial in the optimization of radiation protection of patients and for follow-up studies.
引用
收藏
页码:N375 / N383
页数:9
相关论文
共 21 条
[1]  
[Anonymous], 1975, REPORT TASK GROUP RE, pxix
[2]  
[Anonymous], 2003, Ann ICRP, V32, P3
[3]   Determinants of thyroid volume in healthy French adults participating in the SU.VI.MAX cohort [J].
Barrère, X ;
Valeix, P ;
Preziosi, P ;
Bensimon, M ;
Pelletier, B ;
Galan, P ;
Hercberg, S .
CLINICAL ENDOCRINOLOGY, 2000, 52 (03) :273-278
[4]   A software tool for modification of human voxel models used for application in radiation protection [J].
Becker, Janine ;
Zankl, Maria ;
Petoussi-Henss, Nina .
PHYSICS IN MEDICINE AND BIOLOGY, 2007, 52 (09) :N195-N205
[5]   A METHOD FOR REGISTRATION OF 3-D SHAPES [J].
BESL, PJ ;
MCKAY, ND .
IEEE TRANSACTIONS ON PATTERN ANALYSIS AND MACHINE INTELLIGENCE, 1992, 14 (02) :239-256
[6]   Estimation of the radiation dose delivered to any point outside the target volume per patient treated with external beam radiotherapy [J].
Diallo, I ;
Lamon, A ;
Shamsaldin, A ;
Grimaud, E ;
deVathaire, F ;
Chavaudra, J .
RADIOTHERAPY AND ONCOLOGY, 1996, 38 (03) :269-271
[7]   FDTD calculations of specific energy absorption rate in a seated voxel model of the human body from 10 MHz to 3 GHz [J].
Findlay, R. P. ;
Dimbylow, P. J. .
PHYSICS IN MEDICINE AND BIOLOGY, 2006, 51 (09) :2339-2352
[8]   A MATHEMATICAL CHILD PHANTOM FOR THE CALCULATION OF DOSE TO THE ORGANS AT RISK [J].
FRANCOIS, P ;
BEURTHERET, C ;
DUTREIX, A ;
DEVATHAIRE, F .
MEDICAL PHYSICS, 1988, 15 (03) :328-333
[9]   Computation of electromagnetic fields for high-frequency magnetic resonance imaging applications [J].
Jin, JM ;
Chen, J ;
Chew, WC ;
Gan, H ;
Magin, RL ;
Dimbylow, PJ .
PHYSICS IN MEDICINE AND BIOLOGY, 1996, 41 (12) :2719-2738
[10]   MAX06 and FAX06: update of two adult human phantoms for radiation protection dosimetry [J].
Kramer, R. ;
Khoury, H. J. ;
Vieira, J. W. ;
Lima, V. J. M. .
PHYSICS IN MEDICINE AND BIOLOGY, 2006, 51 (14) :3331-3346