Arterial elastic properties and cardiovascular risk/event

被引:62
作者
Cheng, KS
Baker, CR
Hamilton, G
Hoeks, APG
Seifalian, AM
机构
[1] UCL, Royal Free & Univ Coll, Sch Med, Dept Surg,Cardiovasc Haemodynam Unit, London NW3 2QG, England
[2] Royal Free Hosp, London NW3 2QG, England
[3] Maastricht Univ, Dept Biophys, Cardiovasc Res Inst Maastricht, Maastricht, Netherlands
关键词
elastic; compliance; gender; blood pressure; diabetes; heart disease; renal disease; age; sex; hypertension; pulse wave velocity; hypercholesterolaemia; peripheral vascular disease; stiffness;
D O I
10.1053/ejvs.2002.1756
中图分类号
R61 [外科手术学];
学科分类号
摘要
Cardiovascular disease is a major cause of morbidity and mortality in the western world. There is convincing evidence that the elastic properties, particularly of large arteries, are impaired in the presence of cardiovascular disease and risk factors such as cigarette smoking, hypertension, diabetes and ageing. Evidence is also emerging that treatment of these risk factors is associated with an improvement in the elastic properties, mirrored by a reduction in the cardiovascular risk and events. The main problems associated with arterial elasticity are the multiple definitions and methods of measurement and the problem of obtaining reliable nearby blood pressure measurement. Nevertheless, duplex estimation appears to be a non-invasive, accurate and reliable method of defining these properties. This method is broadly used as a research tool, but there is a good case for its use in clinical practice, particularly in the screening of patients at risk of cardiovascular events.
引用
收藏
页码:383 / 397
页数:15
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