Identification of a susceptibility locus for migraine with and without aura on 6p12.2-p21.1

被引：66

作者：

Carlsson, A

Forsgren, L

Nylander, PO

Hellman, U

Forsman-Semb, K

Holmgren, G

Holmberg, D

Holmberg, M

机构：

[1] Umea Univ, Umea Ctr Mol Med, Umea, Sweden

[2] Umea Univ, Dept Neurol, S-90187 Umea, Sweden

[3] Umea Univ, Dept Med Biosci Clin Genet, Umea, Sweden

[4] Linkoping Univ, Dept Neurosci & Locomot, Linkoping, Sweden

[5] Kalmar Hosp, Dept Psychiat, Kalmar, Sweden

来源：

NEUROLOGY | 2002年 / 59卷 / 11期

关键词：

D O I：

10.1212/01.WNL.0000036617.04943.96

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Migraine is the most common type of chronic episodic headache. To find novel susceptibility genes for familial migraine with and without aura, a genomewide screen was performed in a large family from northern Sweden. Evidence of linkage was obtained on chromosome 6p12.2-p21.1, with a maximum two-point lod score of 5.41 for marker D6S452. The patients with migraine shared a common haplotype of 10 Mb between markers D6S1650 and D6S1960.

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页码：1804 / 1807

页数：4

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