Mucociliary clearance and buffered hypertonic saline solution

被引:174
作者
Talbot, AR
Herr, TM
Parsons, DS
机构
[1] UNIV MISSOURI,SCH MED,DIV OTOLARYNGOL,COLUMBIA,MO 65212
[2] SYDNEY HOSP,ENT DEPT,SYDNEY,NSW,AUSTRALIA
关键词
D O I
10.1097/00005537-199704000-00013
中图分类号
R-3 [医学研究方法]; R3 [基础医学];
学科分类号
1001 ;
摘要
Nasal irrigations have been used for centuries without any scientific data to determine efficacy. For 10 years, the senior author has used buffered hypertonic saline nasal irrigation for patients with acute/chronic sinusitis and for those having undergone sinus surgery, A simple study was undertaken using volunteers without any significant sinonasal disease. Patients served as their own control using a saccharin clearance test before any nasal irrigation was used. Patients then used one of two solutions to irrigate their nose-buffered normal saline or buffered hypertonic saline-and were then retested. On a separate day, the control test was repeated, followed by irrigation with the alternate solution and a second saccharin clearance test. The outcome showed buffered hypertonic saline nasal irrigation to improve mucociliary transit times of saccharin, while buffered normal saline had no such effect.
引用
收藏
页码:500 / 503
页数:4
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