A novel one-pot conversion of amines to homologated esters in poly(ethylene glycol)

被引：19

作者：

Chandrasekhar, S. ^{[1
]}

Reddy, G. Pavan Kumar ^{[1
]}

Nagesh, Ch. ^{[1
]}

Reddy, Ch. Raji ^{[1
]}

机构：

[1] Indian Inst Chem Technol, Hyderabad 500007, Andhra Pradesh, India

来源：

TETRAHEDRON LETTERS | 2007年 / 48卷 / 07期

关键词：

palladium; one-pot reaction; poly(ethylene glycol); amines; esters;

D O I：

10.1016/j.tetlet.2006.12.035

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The first deaminative homologation of amines (-CH2NH2) to esters (-CH2CH2COOEt) in one-pot is reported. The reaction proceeds through, formation of an aldehyde from an amine in the presence of Pd/C as catalyst followed by Wittig reaction and catalytic hydrogenation using poly(ethylene glycol) as the solvent in one-pot. (c) 2007 Elsevier Ltd. All rights reserved.

引用

页码：1269 / 1271

页数：3

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