Bacterial ureases in infectious diseases

被引：276

作者：

Burne, RA ^{[1
]}

Chen, YYM ^{[1
]}

机构：

[1] Univ Rochester, Sch Med & Dent, Ctr Oral Biol, Dept Microbiol & Immunol, Rochester, NY 14642 USA

来源：

MICROBES AND INFECTION | 2000年 / 2卷 / 05期

关键词：

Helicobacter; oral microbes; ecology; pathogenesis; urinary tract;

D O I：

10.1016/S1286-4579(00)00312-9

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Ureases are multi-subunit, nickel-containing enzymes that catalyze the hydrolysis of urea to carbon dioxide and ammonia. This brief review discusses the biochemistry and genetics of bacterial ureases and outlines the roles of urea metabolism in microbial ecology and pathogenesis of some of the principle ureolytic species affecting human health. (C) 2000 Editions scientifiques et medicales Elsevier SAS.

引用

页码：533 / 542

页数：10

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