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The current status of antiparasite chemotherapy

被引：72
作者：
Croft, SL
机构：
来源：
PARASITOLOGY | 1997年 / 114卷
关键词：
D O I：
10.1017/S0031182097001182
中图分类号：
R38 [医学寄生虫学]; Q [生物科学];
学科分类号：
07 ; 0710 ; 09 ; 100103 ;
摘要：
Currently used antiparasitic drugs, including benzimidazoles, nitroimidazoles, avermectins, polyene ionophores, hydroxynaphthoquinones and sesquiterpene lactones, were identified through the empirical route to drug discovery. The modern rational approach to drug design is focused upon the structure and function of biochemical and molecular targets. The requisite pharmacological properties for new anti-parasite drugs should not be ignored in this process.
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页码：S3 / S15
页数：13
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