Cigarette smoking: An undertreated risk factor for cardiovascular disease

被引:198
作者
Erhardt, Leif [1 ]
机构
[1] Lund Univ, Malmo Univ Hosp, Dept Cardiol, S-21138 Malmo, Sweden
关键词
Cardiovascular disease; Risk factors; Smoking; Smoking cessation; Pharmacotherapy; NICOTINE REPLACEMENT THERAPY; ACUTE MYOCARDIAL-INFARCTION; CORONARY-HEART-DISEASE; COST-EFFECTIVENESS; REDUCES MORTALITY; GLOBAL MORTALITY; GENERAL-PRACTICE; BUPROPION SR; OXIDIZED LDL; 52; COUNTRIES;
D O I
10.1016/j.atherosclerosis.2009.01.007
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Smoking and other forms of tobacco use are major risk factors for cardiovascular disease. The effect of cigarette smokingon cardiovascular health is evident even at the lowest levels of exposure. Yet, the adverse effects of smoking are reversible, with cardiovascular risk decreasing substantially within the first 2 years of smoking cessation. Significantly, the mortality from coronary heart disease is reduced more through smoking cessation than by other secondary preventive therapies such as cholesterol lowering. Smoking cessation is a highly effective way to improve cardiovascular health in smokers and extremely cost-effective. However, smoking cessation therapies are not implemented maximally if they are implemented at all, perhaps because smoking is seen as a lifestyle choice or because smokers frequently relapse, as indicated by very low long-term quit rates. Too often, healthcare professionals, including lipidologists and cardiologists, do little to address their patients' smoking status, in spite of its impact on cardiovascular health. With the advent of new therapies to treat the nicotine addiction that results from smoking and other tobacco use, it is hoped that physicians will be more proactive in encouraging and implementing smoking cessation programs for their patients, with the goal of increasing long-term quit rates, and reducing the morbidity and mortality associated with cardiovascular disease. (C) 2009 Elsevier Ireland Ltd. All rights reserved.
引用
收藏
页码:23 / 32
页数:10
相关论文
共 96 条
[1]   The management of acute myocardial infarction in developing countries [J].
Abdallah, Mouhamad H. ;
Arnaout, Samir ;
Karrowni, Wassef ;
Dakik, Habib A. .
INTERNATIONAL JOURNAL OF CARDIOLOGY, 2006, 111 (02) :189-194
[2]  
Am Diabetes Assoc, 2006, DIABETES CARE, V29, pS4
[3]  
[Anonymous], 2006, MMWR MORB MORTAL WKL, V56, P1157
[4]  
[Anonymous], 2002, morbidity and mortality weekly report, V51, P642
[5]   Smoking cessation and cardiovascular disease risk factors: Results from the Third National Health and Nutrition Examination Survey [J].
Bakhru, A ;
Erlinger, TP .
PLOS MEDICINE, 2005, 2 (06) :528-536
[6]   Psychosocial interventions for smoking cessation in patients with coronary heart disease [J].
Barth, J. ;
Critchley, J. ;
Bengel, J. .
COCHRANE DATABASE OF SYSTEMATIC REVIEWS, 2008, (01)
[7]   Dysfunctional endothelial nitric oxide biosynthesis in healthy smokers with impaired endothelium-dependent vasodilatation [J].
Barua, RS ;
Ambrose, JA ;
Eales-Reynolds, LJ ;
DeVoe, MC ;
Zervas, JG ;
Saha, DC .
CIRCULATION, 2001, 104 (16) :1905-1910
[8]   Cardiovascular toxicity of nicotine: Implications for nicotine replacement therapy [J].
Benowitz, NL ;
Gourlay, SG .
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 1997, 29 (07) :1422-1431
[9]   Evaluation of the safety of bupropion (Zyban) for smoking cessation from experience gained in general practice use in England in 2000 [J].
Boshier, A ;
Wilton, LV ;
Shakir, SAW .
EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY, 2003, 59 (10) :767-773
[10]   Weight gain and cardiovascular risk factors during smoking cessation with bupropion or nicotine [J].
Botella-Carretero, JI ;
Escobar-Morreale, HF ;
Martín, I ;
Valero, AM ;
Alvarez, F ;
García, G ;
Varela, C ;
Cantarero, M .
HORMONE AND METABOLIC RESEARCH, 2004, 36 (03) :178-182