A versatile synthesis of 4-aryl tetrahydropyridines via palladium mediated Suzuki cross-coupling with cyclic vinyl boronates

被引：47

作者：

Eastwood, PR ^{[1
]}

机构：

[1] Aventis Pharma, Discovery Chem, Dagenham RM10 7XS, Essex, England

来源：

TETRAHEDRON LETTERS | 2000年 / 41卷 / 19期

关键词：

Suzuki reactions; piperidines; palladium;

D O I：

10.1016/S0040-4039(00)00447-0

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A simple preparation of cyclic vinyl boronates derived from the vinyl triflates of N-protected tetrahydropyridines is described. Suzuki coupling of the boronates with aryl bromides, iodides and triflates proceeds in good yield to give 4-aryl tetrahydropyridines. (C) 2000 Elsevier Science Ltd. All rights reserved.

引用

页码：3705 / 3708

页数：4

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