Remote daily real-time monitoring in patients with COPD - A feasibility study using a novel device

被引:44
作者
Sund, Z. M. [1 ]
Powell, T. [1 ]
Greenwood, R. [1 ]
Jarad, N. A. [1 ]
机构
[1] Bristol Royal Infirm & Gen Hosp, Dept Resp Med, Bristol BS2 8HW, Avon, England
关键词
Acute exacerbations of chronic obstructive pulmonary disease; (AECOPD); Chronic obstructive pulmonary disease (COPD); Daily electronic monitoring; OBSTRUCTIVE PULMONARY-DISEASE; QUALITY-OF-LIFE; FLUTICASONE PROPIONATE; HEALTH-STATUS; EXACERBATIONS; TIOTROPIUM; THERAPY;
D O I
10.1016/j.rmed.2009.03.017
中图分类号
R5 [内科学];
学科分类号
100201 [内科学];
摘要
New technologies have allowed remote real-time electronic recording of symptoms and spirometry. The feasibility of utilising this technology in COPI) patients has not been investigated. This is a feasibility study. The primary objective is to determine whether the use of an electronic diary with a portable spirometer can be performed by COPI) patients with a moderate to severe disease. Secondary objectives are to investigate the value of this method in early detection of acute exacerbations of COPD (AECOPD). In this 6-month study, 18 patients recorded daily their symptom score and spirometry. Data was sent on real time. AECOPD which was defined according to pre-set criteria were noted. Spirometry values and scores for health-related quality of life were compared between the start and the end of the study. Hospitalisation rate due to AECOPD was compared with a parallel period in the previous year. On average, patients were able to record 77% of their total. study days. The system detected 73% of AECOPD. In further 27% of AECOPD patients sought treatment although the change in symptoms did not meet AECOPD definition. The number of COPD-related hospitalisations significantly reduced compared to the previous year. There was a significant increase in FEV1 and FVC from the start to the end of the study. The remote monitoring device used in this study can be used in COPD patients. AECOPD was detected early in the majority of cases. Hospitalisation rate due to AECOPD was reduced and FEV1 and FVC values increased during the study. (C) 2009 Elsevier Ltd. All rights reserved.
引用
收藏
页码:1320 / 1328
页数:9
相关论文
共 28 条
[1]
[Anonymous], 1994, Respir Med, V88, P165
[2]
ANTIBIOTIC-THERAPY IN EXACERBATIONS OF CHRONIC OBSTRUCTIVE PULMONARY-DISEASE [J].
ANTHONISEN, NR ;
MANFREDA, J ;
WARREN, CPW ;
HERSHFIELD, ES ;
HARDING, GKM ;
NELSON, NA .
ANNALS OF INTERNAL MEDICINE, 1987, 106 (02) :196-204
[3]
*BTS NICE, 2004, THORAX S1, V59
[4]
Randomised, double blind, placebo controlled study of fluticasone propionate in patients with moderate to severe chronic obstructive pulmonary disease: the ISOLDE trial [J].
Burge, PS ;
Calverley, PMA ;
Jones, PW ;
Spencer, S ;
Anderson, JA ;
Maslen, TK .
BMJ-BRITISH MEDICAL JOURNAL, 2000, 320 (7245) :1297-1303
[5]
COPD exacerbations: definitions and classifications [J].
Burge, S ;
Wedzicha, JA .
EUROPEAN RESPIRATORY JOURNAL, 2003, 21 :46S-53S
[6]
Salmeterol and fluticasone propionate and survival in chronic obstructive pulmonary disease [J].
Calverley, Peter M. A. ;
Anderson, Julie A. ;
Celli, Bartolome ;
Ferguson, Gary T. ;
Jenkins, Christine ;
Jones, Paul W. ;
Yates, Julie C. ;
Vestbo, Jorgen ;
Calverley, P. M. A. ;
Anderson, J. A. ;
Celli, B. ;
Ferguson, G. T. ;
Jenkins, C. ;
Jones, P. W. ;
Knobil, K. ;
Yates, J. C. ;
Vestbo, J. ;
Cherniack, R. ;
Similowski, T. ;
Cleland, J. ;
Whitehead, A. ;
Wise, R. ;
McGarvey, L. ;
John, M. .
NEW ENGLAND JOURNAL OF MEDICINE, 2007, 356 (08) :775-789
[7]
Standards for the diagnosis and treatment of patients with COPD: a summary of the ATS/ERS position paper [J].
Celli, BR ;
MacNee, W ;
Agusti, A ;
Anzueto, A ;
Berg, B ;
Buist, AS ;
Calverley, PMA ;
Chavannes, N ;
Dillard, T ;
Fahy, B ;
Fein, A ;
Heffner, J ;
Lareau, S ;
Meek, P ;
Martinez, F ;
McNicholas, W ;
Muris, J ;
Austegard, E ;
Pauwels, R ;
Rennard, S ;
Rossi, A ;
Siafakas, N ;
Tiep, B ;
Vestbo, J ;
Wouters, E ;
ZuWallack, R .
EUROPEAN RESPIRATORY JOURNAL, 2004, 23 (06) :932-946
[8]
CELLI BR, 1995, AM J RESP CRIT CARE, V152, pS77
[9]
COPD exacerbations 1: Epidemiology [J].
Donaldson, GC ;
Wedzicha, JA .
THORAX, 2006, 61 (02) :164-168
[10]
Relationship between exacerbation frequency and lung function decline in chronic obstructive pulmonary disease [J].
Donaldson, GC ;
Seemungal, TAR ;
Bhowmik, A ;
Wedzicha, JA .
THORAX, 2002, 57 (10) :847-852